探讨多索茶碱与噻托溴铵粉联合治疗慢性阻塞性肺疾病对肺功能的影响
2016-08-13马小梅镇江市中西医结合医院江苏镇江212000
马小梅镇江市中西医结合医院,江苏镇江 212000
探讨多索茶碱与噻托溴铵粉联合治疗慢性阻塞性肺疾病对肺功能的影响
马小梅
镇江市中西医结合医院,江苏镇江212000
目的 探讨多索茶碱与噻托溴铵粉联合治疗慢阻肺对肺功能的影响。方法 方便选取该院自2013年12月—2015年12月收治的慢阻肺患者48例,以随机分配法对患者进行分组处理,观察组及对照组患者均为24例。对照组患者单纯以多索茶碱进行治疗;观察组患者在多索茶碱治疗基础上联合噻托溴铵粉进行治疗,分析比较两组患者的临床疗效。结果①治疗总有效率比较:观察组为95.8%(23/24);对照组为75%(18/24),组间比较差异有统计学意义(P<0.05);②肺功能指标改善上:治疗后,以观察组患者的FVC、FEV1、FEV1/FVC指标改善更显著,组间比较差异有统计学意义P<0.05。结论 多索茶碱与噻托溴铵粉联合治疗慢阻肺临床效果显著,优于单项多索茶碱治疗。
多索茶碱;噻托溴铵粉;慢阻肺;肺功能;影响
[Abstract]Objective To investigate the effect of doxofylline and tiotropium bromide powder combined with the treatment of chronic obstructive pulmonary disease effect on lung function.Methods In our hospital from December 2013 to December 2015,48 patients with chronic obstructive pulmonary disease were divided into two groups.The patients in the observation group and the control group were treated with 24 cases.The control group were treated with doxofylline treatment;observation group patients in doxofylline treatment based on combined with thiazide tiotropium bromide powder treatment and analysis were compared between the two groups of patients with clinical curative effect.Results①The total efficiency of treatment:observation group was 95.8%(23/24);control group was 75%(18/24),comparison between the two groups(P<0.05);②pulmonary function improvement:after treatment,to observation group patients with FVC,FEV1,FEV1/FVC index improved more significantly,the group is P<0.05.Conclusion Doxofylline and tiotropium bromide powder combined treatment of COPD clinical effect significantly,better than the single doxofylline treatment.
[Key words]Doxofylline;Tiotropium powder;Chronic obstructive pulmonary disease;Pulmonary function;Influence
慢阻肺是以气流受限不完全可逆、呈进行性发展为特征的一类呼吸系统疾病,该病多发生于中老年人群,发病率及致死率均较高[1]。若不对患者实施针对有效的临床治疗和干预,可导致病情加重,严重损伤肺功能。对于慢阻肺的治疗,临床上多以药物保守治疗为主。笔者除了有效控制患者病情发展外,同时对患者的肺功能进行干预,往往可获得更好的预后[2]。在该次调查中,该院以2013年12月—2015年12月期间在该院接受治疗的48例慢阻肺患者为例,将分析多索茶碱与噻托溴铵粉联合治疗的应用效果,现报道如下。……
