鼻塞式持续气道正压通气辅助治疗重症毛细支气管炎临床观察
2016-08-03张瑛
张瑛

【摘要】 目的 探讨鼻塞式持续气道正压通气(CPAP)治疗重症毛细支气管炎患儿的疗效。方法 100例重症毛细支气管炎患儿随机分为治疗组40例与对照组60例。治疗组在常规综合治疗的基础上给予鼻塞式CPAP辅助治疗, 对照组在综合治疗的基础上给予鼻导管或头罩吸氧。比较两组治疗3、5、7 d后的治疗效果。结果 治疗组患儿治疗3、5、7 d后总有效率均高于对照组, 差异均有统计学意义(P<0.01)。结论 鼻塞式CPAP辅助治疗重症毛细支气管炎疗效显著, 值得推广应用。
【关键词】 重症毛细支气管炎;持续气道正压通气;疗效
DOI:10.14163/j.cnki.11-5547/r.2016.18.007
【Abstract】 Objective To investigate curative effect by nasal continuous positive airway pressure (CPAP) in the treatment of severe capillary bronchitis children. Methods A total of 100 severe capillary bronchitis children were randomly divided into treatment group with 40 cases and control group with 60 cases. The treatment group received nasal CPAP as adjuvant therapy in addition to conventional comprehensive treatment, and the control group received nasal catheter or hood oxygen inhalation in addition to conventional comprehensive treatment. Curative effects in 3, 5, 7 d after treatment were compared between the two groups. Results The treatment group had all higher total effective rate in 3, 5, 7 d after treatment than the control group, and their differences all had statistical significance (P<0.01). Conclusion Nasal CPAP provides precisely curative effect as adjuvant therapy of severe capillary bronchitis, and it is worth promoting and applying.
【Key words】 Severe capillary bronchitis; Continuous positive airway pressure; Curative effect
毛细支气管炎是好发于婴幼儿时期的特殊类型的支气管炎, 临床上主要表现为喘憋烦躁、拒奶等, 严重时可出现呼吸困难、发绀等危及生命的情况。此外, 喘憋严重时可并发呼吸衰竭、心力衰竭、脑水肿、消化道出血等, 甚至引起死亡。迅速解除呼吸道梗阻、改善通气、控制喘憋发作是临床上治疗毛细支气管炎的关键。本科2011年3月~2014年3月在综合治疗的基础上及早给予鼻塞式CPAP辅助治疗40例重症毛细支气管炎患儿, 取得良好效果, 现报告如下。
1 资料与方法
1. 1 一般资料 根据《诸福棠实用儿科学》第7版《小儿肺炎防治方案诊断依据》毛细支气管炎诊断标准[1], 选择本科2011年3月~2014年3月收治的重症毛细支气管炎患儿100例,
其中, 男59例, 女41例;年龄1~3个月60例, 3~6个月30例, 6个月~1岁8例, 1~2岁2例。随机分为治疗组40例与对照组60例。
1. 2 治疗方法 所有患儿入院后立即给予心电监护、吸氧, 密切观察体温、呼吸、心率及经皮测氧饱和度;积极完善肺部听诊及X线胸片、血尿便常规、C反应蛋白、肝功、心肌酶、肾功能、血气分析等检查明确病变评估病情。……
