李成义 强正泽 王燕 王明伟 李硕

摘要：目的 以甘肃不同产区红芪为研究对象，红芪中微量元素含量为评价指标，评价甘肃不同产区红芪质量，为红芪质量标准的制定提供参考依据。方法 采用火焰原子吸收分光光度法测定甘肃不同产区红芪中铁、铜、钙、锰、锌、镁、铬、钴、钠、锂、镍、钾微量元素含量，应用SPSS21.0软件对数据进行因子分析，采用主成分提取公因子，建立质量综合排名分析函数。结果 提取了3个公因子F1、F2、F3，质量评价函数为Y=0.657F1+0.119F2+0.089F3；铬、锂、钴、铜、锌、铁、镁是影响红芪质量的特征性元素；以微量元素评价红芪质量时，野生红芪的质量优于栽培红芪的质量，质量排名结果与陇南为红芪主产区相符，定西地区部分样品质量较优。结论 以微量元素评价红芪质量表征了不同产区红芪质量之间的差异性，结果较为合理。

关键词：不同产区；红芪；微量元素；质量评价

DOI：10.3969/j.issn.1005-5304.2016.06.024

中图分类号：R284.1 文献标识码：A 文章编号：1005-5304（2016）06-0092-07

Abstract： Objective To evaluate the quality of Hedysari Radix from different producing areas in Gansu Province by setting Hedysari Radix from different producing areas in Gansu Province as study subjects and trace elements in Hedysari Radix as evaluation indexes； To provide the references for establishment of the quality standards of Hedysari Radix. Methods The content of Fe， Cu， Ca， Mn， Zn， Mg， Cr， Co， Na， Li， Ni and K in Hedysari Radix were detected by using flame atomic absorbption method. Data were analyzed by the factor analysis conducted by SPSS21.0 software. The common factors were extracted by principal component and analytic function for quality comprehensive ranking was established. Results Three common factors were extracted， namely F1， F2， and F3. The quality function was Y=0.657F1+0.119F2+0.089F3. Cr， Li， Co， Cu， Zn， Fe and Mg were the characteristic trace elements of Hedysari Radix that could affect the quality of Hedysari Radix. When the quality of Hedysari Radix was evaluated by the contents of trace elements， the quality of wild Hedysari Radix were better than cultivated Hedysari Radix and the quality rank was consistent with the idea that Longnan is the main producing area of Hedysari Radix. The quality of samples from Dingxi area was better. Conclusion The quality evaluation of Hedysari Radix based on trace elements shows the differences in Hedysari Radix from different producing areas in Gansu Province and the results are relatively reasonable.

Key words： different producing areas； Hedysari Radix； trace elements； quality evaluation

红芪为豆科植物多序岩黄芪Hedysarum polybotrys Hand.-Mazz.的干燥根，是甘肃地产药材之一，最早记录在《神农本草经》黄芪项下，用药历史悠久，具有补气固表、利尿托毒等功效[1]。古代将红芪分为上中下三品进行质量评价。《本草蒙筌》记载：“……种有三品，治无两般。木芪茎短理横，功力殊劣，此为下品。……水芪生白水、赤水二乡，俱属陇西，白水颇胜，此为中品。绵芪出山西沁州绵上，此品极佳，为上品。”随着许多现代学科的交叉，中药质量评价的方法趋向于代谢组学的方法[2]、选择离子集成谱的方法[3]、色谱联用技术[4]、一