谭玉文

[摘要] 目的 分析无创正压通气对冠心病并OSAHS患者心律失常的影响。 方法 回顾性分析2012年9月—2014年9月该院收治的70例冠心病并OSAHS患者临床资料，根据治疗时所采用不同治疗方案分为两组，对照组30例患者行常规治疗，研究组40例患者行无创正压通气治疗，记录并分析数据。 结果 研究组室性、室上性的心律失常均低于对照组，且研究组LVEDs、LVEDd均低于对照组；研究组不良事件总发生率5.00%显著低于对照组46.67%，两组差异有统计学意义（P<0.05）。 结论 冠心病并OSAHS行无创正压通气具确切疗效，可在改善心功能基础上减少心律失常。

[关键词] 无创正压通气；冠心病；阻塞性睡眠呼吸暂停低通气综合征；心律失常

[中图分类号] R541.4 [文献标识码] A [文章编号] 1674-0742（2016）02（b）-0177-02

[Abstract] Objective To analyze the effect of non-invasive positive pressure ventilation on arrhythmia in patients with coronary heart disease complicated by OSAHS. Methods The clinical data of 70 cases of patients with coronary heart disease complicated by OSAHS treated in our hospital from September 2012 to September 2014 were retrospectively analyzed and the patients were divided into two groups according to the different treatment programs， the control group（n=30） were treated with conventional method， the research group（n=40） were treated with non-invasive positive pressure ventilation， the data were recorded and analyzed. Results The ventricular arrhythmia and supraventricular arrhythmia in the research group were lower than those in the control group， and the LVEDs and LVEDd in the research group were lower than those in the control group， the total incidence of adverse events in the research group was obviously lower than that in the control group（5.00% vs 46.67%）， all differences between the two groups were statistically significant（P<0.05）. Conclusion The curative effect of non-invasive positive pressure ventilation treatment for coronary heart disease complicated by OSAHS is definite， and it can reduce arrhythmia on the basis of improving the heart function.

[Key words] Non-invasive positive pressure ventilation； Coronary heart disease； Obstructive sleep apnea hypopnea syndrome； Arrhythmia

阻塞性睡眠呼吸暂停低通气综合征（OSAHS）属于睡眠呼吸性疾病，其病情进展可致多脏器损伤，并成为诱发心脑血管疾病的高危因素，冠心病属于其多发合并症，但目前针对冠心病并OSAHS治疗的研究较少[1]。为探究冠心病并阻塞性睡眠呼吸暂停低通气综合征应用无创正压通气治疗方案的疗效，同时提供相关疾病以后临床治疗的依据，该研究回顾性分析2012年9月—2014年9月该院收治的70例患者临床资料，以探讨无创正压通气对该合并症患者心律失常的影响，现报道如下。

1 资料与方法

1.1 一般资料

回顾性分析2012年9月—2014年9月该院收治的70例冠心病并OSAHS患者临床资料，均符合《阻塞性睡眠呼吸暂停低通气综合征诊治指南》诊断标准并经冠脉造影确诊冠心病[2]。根据治疗时所采用不同治疗方案分为两组，对照组30例患者，男14例，女16例，年龄46～75岁，平均（67.15±7.27）岁；……