半夏泻心汤治疗慢性萎缩性胃炎
2016-02-05高仲英
高仲英
半夏泻心汤治疗慢性萎缩性胃炎
高仲英
目的 探讨半夏泻心汤加味治疗慢性萎缩性胃炎(CAG)的效果。方法 选择本院80例CAG患者,随机分为两组,观察组(应用加味半夏泻心汤治疗)及对照组(应用奥美拉唑、克拉霉素、阿莫西林三联疗法治疗),对比两组治疗总有效率及中医症状积分。结果 1个疗程后,观察组患者治疗总有效率为95.0%,高于对照组85.0%(P<0.05)。观察组中医症状积分低于对照组(P<0.05)。结论 应用加味半夏泻心汤治疗CAG对提高患者临床疗效,缓解患者临床症状均具有重要意义。
慢性萎缩性胃炎;加味半夏泻心汤;中医症状积分
【Abstract】Objective To investigate banxiaxiexin decoction in treatment of chronic atrophic gastritis(CAG). Methods 80 cases of CAG in our hospital were randomly divided into two groups,the observation group(received modified application banxiaxiexintang treatment)and control group(received omeprazole,clarithromycin and amoxicillin triple therapy),the total efficiency of treatment group and TCM symptom scores in two groups were compared. Results After a course of treatment,patients in the observation group total effective rate was 95.0%,significantly higher than control group was 85.0%(P<0.05). TCM symptom score of observation group was significantly lower than the control group(P<0.05). Conclusion Modified banxiaxiexin decoction in treatment of CAG can improve the clinical efficacy in patients,alleviate clinical symptoms are of great significance. 【Key words】 Chronic atrophic gastritis,Modified banxiaxiexintang,TCM symptom score
CAG是一种以胃黏膜固有腺体萎缩、减少、消失为主要特征的消化系统疾病,其发生率约为7.5%,若得不到及时治疗可发展为胃癌[1-2]。本文考察了半夏泻心汤治疗CAG的效果,以期为该病治疗提供参考依据,报道如下。
1 资料与方法
1.1一般资料
2015年3月~2016年2月按照治疗方案不同将我院80例CAG患者分为观察组及对照组(n=40)。入组标准:符合《实用内科学》[3]CAG相关诊断标准,且经胃镜检查确诊;知情同意。排除标准:研究药物过敏者;哺乳期、妊娠期女性;合并消化道溃疡者;合并严重肾、肝、心疾病者。观察组,男21例,女19例;年龄23~62岁,平均(46.3±5.4)岁;病程8个月~12年,平均(5.21±0.57)年。对照组,男22例,女18例;年龄24~64岁,平均(47.1±5.6)岁;病程10个月~13年,平均(5.41±0.59)年。组间病程、年龄及性别等基线资料对比,P>0.05,具备可比性。
1.2方法
对照组采用奥美拉唑(20 mg/次,2次/d,早晚空腹口服)、克拉霉素(0.25 g/次,2次/d,饭后口服)及阿莫西林(0.5 g/次,3次/d,饭后口服)三联疗法,连续用药30 d;……
