韩传映　方勤

[摘要] 目的 对小儿咳嗽变异性哮喘的临床诊断和治疗进行探讨和分析。 方法 随机选取2014 年2 月—2015年3月期间在该院接受治疗的小儿咳嗽变异性哮喘患儿52 例，按照不同的治疗方法平均分为两组，喷雾组患者通过二丙酸培氯米松气雾剂进行治疗，口服组的治疗方法则是服用孟鲁司特钠和盐酸丙卡特罗，将两组患者的治疗效果进行对比，探讨小儿咳嗽变异性哮喘的治疗效果。 结果 数据结果显示，采用二丙酸培氯米松气雾剂进行治疗的喷雾组（88.5%）患者治疗有效率比口服组患者（96.2%）低，两组数据差异有统计学意义（χ2=6.786，P=0.0012）。 结论 提高小儿咳嗽变异性哮喘诊断的准确性，从而能够及时有效地治疗；通过服用孟鲁司特钠联合盐酸丙卡特罗治疗小儿咳嗽变异性哮喘临床疗效显著，显效快、复发率低，更适合临床小儿咳嗽变异性哮喘的治疗。

[关键词] 小儿咳嗽变异性哮喘；临床诊断；治疗

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2015）09（c）-0051-02

[Abstract] Objective To discuss and analyze clinical diagnosis and treatment of infantile cough variant asthma. Methods 52 patients with infantile cough variant asthma treated in this hospital from February 2014 and March 2015 were randomly selected and divided evenly into two groups according to methods used. Patients in the group were treated with beclomethasone dipropionate aerosol spray group， while those in the oral group were administrated with montelukast and procaterol hydrochloride orally. We compared and discussed the efficacy of the two treatments. Results The efficacy （88.5% vs 96.2%） was lower in the spray group than in the oral group， and the difference was statistically significant（χ2=6.786， P=0.0012）. Conclusion Accurate diagnosis is necessary for the timely and effective treatment of infantile cough variant asthma， and for this disease， oral administration of montelukast and procaterol hydrochloride can bring remarkable effect with rapid response and low recurrence rate， and is more suitable.

[Key words] Cough variant asthma； Clinical diagnosis； Treatment

小儿咳嗽变异性哮喘在临床上较普遍，发病主要原因有：幼儿体质相对薄弱，免疫力差、遗传因数、小儿呼吸系统发育不完善、个人过敏体质等[1]。小儿咳嗽变异性哮喘临床常表现为持续咳嗽，和其他呼吸系统疾病较为相似，容易发生误诊漏诊等情况，从而延误病情导致严重后果。因此探究小儿咳嗽变异性哮喘的临床诊断，并进行及时有效的治疗极为重要。该研究对2014 年4月—2015年3月期间该院接受治疗的患儿进行研究，结果显示孟鲁司特钠联合盐酸丙卡特罗治疗小儿咳嗽变异性哮喘临床疗效显著，现报道如下。……