4新生儿中毒性红斑的发病率及相关发病因素调查
2015-10-21刘慧焕李焕平郭果香关宏亮王福军田华辛燕
刘慧焕 李焕平 郭果香 关宏亮 王福军 田华 辛燕
【摘要】目的:调查本地区新生儿中毒性红斑的发病率,探讨影响新生儿中毒性红斑相关发病因素。方法:调查2011年3月至2012年8 月产科生产的新生儿,对可能影响新生儿中毒性红斑发病的各个变量进行单因素非条件logistic回归分析,再以单因素logistic回归有统计意义的因素为自变量,逐步后退法进行多因素非条件logistic回归分析。结果:本地区新生儿中毒性红斑发病率为64.01 %,影响新生儿中毒性红斑发病的因素有:衣物及被褥多少、家中养宠物:新生儿衣物及被褥多比少的患病危险性大,妊娠期间家中养宠物比家中不养宠物患病危险性大。结论:新生儿中毒性红斑皮疹的发生有可能是内外因素的结果。合理指导孕妇妊娠期间的生活习惯及正确护理新生儿可降低新生儿中毒性红斑的发生。
【关键词】 新生儿中毒性红斑; 发病率; 发病因素
【Abstract】 objective: to investigate the incidence of toxic erythema of the newborns in the region, and to explore the pathogenic factors of neonatal toxic erythema. Methods: the survey from March 2011 to August 2012 newborns in obstetrical department, on the incidence of toxic erythema may affect newborns non-conditional logistic regression analysis of factors to each variable, univariate logistic regression had statistical significance factors for argument, gradual retreat method for multivariate unconditional logistic regression analysis. The result: The toxic erythema incidence of neonatus in the region was 64.01%, the factors affecting the incidence of neonatals suffer from toxic erythema including clothing and bedding, household pets. More clothes and beddings, raising pets during pregnancy are more prevalence to suffer from neonatal toxic erythema. Conclusion: Neonatal toxic erythema rash could be the result from internal and external factors. Reasonable guide of the living habits and proper care during and after pregnancy could reduce toxicity in neonatal toxic erythema of the newborns.
【key words 】Erythema; Neonatal toxic erythema , Incidence; Risk factors
【中图分类号】R722.12 【文献标识码】B【文章编号】1004-4949(2015)03-0482-01
新生儿中毒性红斑(Erythema Toxicum Neonatorum ETN)是常见的新生儿皮肤病之一。据报道世界范围内的新生儿均有发病,发病率差别较大,3.7%--72%不等[1] [2] [3] ,发病机制不明[4] [5] ,流行病学及临床特征资料有待完善。近年来的报道新生儿中毒性红斑发病率一直较高,新生儿中毒性红斑常常给患儿家属带来恐慌,我们研究新生儿中毒性红斑的发病率及发病因素为揭示该病的发病机制提供依据,为医务工作者及患儿家属预防新生儿中毒性红斑提供参考。
一 对象与方法
对象:被调查新生儿入选标准:新生儿出生时各项指标均正常, 排除新生儿患其它皮肤病如:脓疱性粟丘疹、接触性皮炎、脂溢性皮炎、新生儿脓疱性黑变病、搽烂、疥疮、坏疽性深脓疱疮、大疱性表皮松解症等。……
