丙泊酚—七氟醚复合诱导在老年人麻醉中的临床探讨
2015-09-28赵李红
赵李红
[摘要] 目的 探讨七氟醚-丙泊酚复合诱导在老年人麻醉中的临床效果。 方法 将随机选取的2013年1月—2014年12月该院收治的100例手术患者随机分为两组,每组50例。对照组运用七氟醚进行治疗,观察组运用七氟醚复合丙泊酚进行治疗,比较对照组和观察组患者术前术中的心率、血压、血氧饱和度、苏醒时间及不良反应发生率。结果 T1时刻,两组的SBP、DBP、HR水平均较T0时刻显著降低(P<0.05),且观察组T1时刻的SBP、DBP、HR水平显著高于对照组,P<0.05;T2时刻,两组患者的SBP、DBP、HR水平均较T1时刻有所提高,观察组T2时刻的SBP、DBP、HR水平均显著低于对照组,P<0.05;两组患者T3、T4时刻的SBP、DBP、HR水平比较均差异无统计学意义(P>0.05)。两组的苏醒时间、苏醒期躁动率比较差异有统计学意义(P< 0.05);两组的恶心、呕吐发生率比较差异无统计学意义(P>0.05)。结论 采用七氟醚-丙泊酚复合诱导老年人麻醉,在手术过程中可以保持循环功能的稳定,而且手术后苏醒时间短,应在临床上大力推广应用。
[关键词] 七氟醚;丙泊酚;老年人;麻醉
[中图分类号] R614 [文献标识码] A [文章编号] 1674-0742(2015)08(c)-0119-03
Propofol Sevoflurane combined Clinical Observation of Anesthesia Induction in the Elderly
ZHAO Li-hong
The Department of Anesthesiology, Suzhou Municipal Hospital,Suzhou, Jiangsu Province, 215000 China
[Abstract] Objective To observe the effects of sevoflurane propofol compound induced in clinical anesthetic effect in the elderly. Methods Randomly 100 cases operation from 2013 January to 2014 December were divided into two groups, 50 cases in each group. The control group using sevoflurane, the observation group with sevoflurane and propofol, compared two groups of patients before surgery in the heart rate, blood pressure, oxygen saturation, the recovery time and the incidence of adverse reactions. Results T1 time, two groups of SBP, DBP, HR level were significantly decreased (P<0.05) T0 moment, T1 moment and the observation group SBP, DBP, HR levels were significantly higher than those in the control group, P<0.05; T2 moment, two groups of patients with SBP, DBP, HR levels were lower than T1 constantly improve, observation group T2 moment, DBP SBP, HR levels were significantly lower than those in the control group, two groups of patients with T3, P<0.05; T4, DBP, HR moment SBP level had no significant difference (P>0.05). The two group of recovery time, restlessness rate had significant difference (P< 0.05); nausea, vomiting two groups compared the incidence of no significant difference (P > 0.05). Conclusion Propofol combined with sevoflurane - induced geriatric anesthesia, to maintain the stability of circulation, and postoperative recovery in a short time, it is worth in the clinical application.
[Key words] Sevoflurane; Propofol; Elderly; Anesthesia
在麻醉诱导期,老年患者血流动力学改变较为明显,会造成多种并发症而出现意外。丙泊酚以及七氟醚属于临床中麻醉诱导、维持的使用较为广泛的药物,用药时往往发生血压降低、心率变慢等症状,尤其是对老年高血压等患者的抑制作用则更加显著[1]。现阶段,作为新型的麻醉药,在临床中丙泊酚应用于麻醉诱导或者ICU危重等患者。该麻醉药物的优点为:苏醒时间短、起效快、完善功能恢复以及术后不良反应较少等。七氟醚对气道影响小,较易调控麻醉深度以及清醒时间,同时对肾等器官和血流动力学影响较小[2],是手术麻醉的最佳方案,还可以维持患者生理功能指标的稳定。该研究随机选择2013年1月—2014年12月该院收治的100例手术患者,观察七氟醚复合丙泊酚在患者麻醉中的临床应用效果,现报道如下。……
