□ 文/本刊记者 唐纲

独家对话重庆海扶医院院长汪炼“捍卫子宫，不分国界！”

□ 文/本刊记者 唐纲

记者：我看了下你们的资料，你们医院采用的核心技术是妇产科教授王智彪及团队发明的海扶超声聚焦刀治疗骨癌、肝癌、乳腺癌及子宫肌瘤等。海扶超声聚焦刀的学术名称叫“高强度聚焦肿瘤治疗系统”。这个“肿瘤”与我们常说的“癌”是什么关系？

汪炼：肿瘤分恶性和良性，而“癌”通常是指恶性肿瘤。

记者：海扶超声聚焦刀我早就听说过，10几年前新闻报道过，当时在世界上引起很大震动。

汪炼：是的。王智彪是一位妇产科教授、博士生导师、海扶超声聚焦刀的第一发明人。他立志于解除妇女的痛苦发明了聚焦刀，而聚焦刀发明后不仅能解除妇女的痛苦，也能解除肿瘤患者的痛苦。

记者：听说人在你们的机器上一“照”病就好了？

汪炼：“照”只是一个形象的说法。聚焦刀类似放大镜聚焦的原理。它利用超声波的组织穿透性和可聚焦性，将低能量的超声波聚焦，在焦点处瞬间产生高温，从而杀灭体内的肿瘤组织，而在焦点外没有组织的损伤，实现了医学一直向往的不开刀、不流血的手术。其专业名词叫“超声消融”。

记者：“照”一下就好了，听起来像神话，真有点不可思议？

汪炼：但这确实是真实的。上世纪40年代，美国科学家Fry兄弟曾梦想“能否将超声波从体外聚焦到体内只杀死肿瘤，而不伤害周围组织和机体的正常功能”，上世纪90年代末，中国重庆的王智彪教授及团队把这个世界性的重大科学问题变成了现实。

迄今，该技术已从重庆走向了世界，先后落户于英国、德国、意大利、西班牙、俄罗斯、韩国、日本等19个国家25个地区的医科大学和医院，治疗子宫肌瘤、子宫腺肌病逾2万例、恶性实体肿瘤逾5万例，中国原始自主创新的高科技术在临床上得到了成功运用。

子宫肌瘤妇女发病率30—50%，生育年龄高达50%。目前多数是切除患者子宫。现在，美国每年有62.2万妇女子宫被切除，中国约有200万妇女子宫被切除。据了解，切除子宫对妇女危害巨大。那么，子宫肌瘤患者应如何应对呢？日前，本刊记者独家对话全球首家子宫肌瘤专病医院——重庆医科大学附一院海扶医院院长汪炼。

重庆海扶医院院长汪炼

记者：这么牛呀？说来还是现实不是神话？

汪炼：牛或不牛，这都是现实。160多年前，发明麻醉技术开启了人体手术治疗史；半个世纪前腔镜技术发明，开启了微创医疗。15年前，王智彪及团队发明了超声聚焦刀技术，由此开启了微无创医疗。这成为世界医疗史上新的里程碑。

记者：你们这个“聚焦刀”针对所有肿瘤，不分恶性和良性吗？

汪炼：是的。良性肿瘤包括：子宫肌瘤、子宫腺肌病、乳腺纤维瘤；恶性肿瘤包括：肝癌、乳腺癌、骨肿瘤、软组织肉瘤、肾癌、胰腺癌等。“聚焦刀”都管用，只要是实体肿瘤，不分良性、恶性。

记者：那现在得了癌症还有必要这么害怕吗？

汪炼：“聚焦刀”是癌症的克星。1998年，小熊（化名）被确诊为骨癌，跑遍全国许多大医院，得到的回答都是“截肢”。当时，她还是一个仅有9岁的小姑娘。1999年8月，海扶医疗团队用“海扶超声聚焦刀”为她进行了治疗，而且是“无创”，不仅保住了患肢，而且健康地活了下来，后来她还上了大学，并成家立业。这样的例子有很多。我们医院可以治疗各种骨癌、肝癌等癌症。人们大可不必得癌色变。

重庆医科大学附一院海扶医院内景

记者：现在，很多医院治疗子宫肌瘤都是手术挖出或子宫切除。你们的这个做法与传统的做法有什么不同？

汪炼：子宫肌瘤妇女发病率达30—50%，生育年龄高达50%。目前多数是手术挖出或子宫切除。现在，美国每年有62.2万妇女子宫切除，中国约有200万妇女子宫切除。挽救子宫比什么都重要。作为医生，关爱生命，就应该从尊重器官开始。

现在，在传统医院做子宫肌瘤手术，一般大概要住院一周，休息1—2个月。我们约有70%的患者有机会选择不开刀的无创治疗。因为没有伤口，恢复快，住院2天左右，回家休息1-2天即可，也可以不住院，以“日间手术”在门诊完成。我们很多的外地病人当天治疗后，第2天就在重庆参加一日游了。

记者：这么简单？我平时感觉到的是，女人们只要一检查到自己得了子宫肌瘤，总是害怕得不得了，甚至以为是得了绝症。没想到操作这么简单。

汪炼：子宫肌瘤是女性最常见的良性肿瘤，育龄期女性发生率可高达50%左右，发展成恶性肿瘤的概率非常小。

记者：有没有典型案例？

汪炼：多了。我刚才说，迄今为止，我们已在全球治疗各种良性肿瘤逾2万例，有国内的，也有国外患者慕名而来。2009年，澳大利亚华人“在水一方”（网名）体检发现多发性子宫肌瘤，其中最大的肌瘤直径7.6公分，此后的时间里肌瘤一直不断长大、增多。到2011年初，肌瘤已经长大至接近11.5公分。在澳大利亚，多家医院的医生建议其直接切除子宫，一劳永逸，然而“在水一方”捍卫子宫的决心从未动摇。直到2011年4月，“在水一方”通过网络了解到海扶超声消融无创治疗子宫肌瘤的方式。2011年9月，“在水一方”从澳大利亚飞往重庆，在我们医院接受了超声消融治疗，成功消融15个肌瘤。手术后三个月，“在水一方”在澳洲复查B超，结果显示最大的肌瘤已从11.50cm缩小到3.9cm（肌瘤体积缩小了70%），其它等症状也得到了明显的改善。B超结果让澳洲医生也为之震撼。如果要想了解更多的案例，可以上我们的网站（www.haifuhospital.com/）查询。

记者：现在，因子宫肌瘤失去子宫的女性越来越多，请问汪院长：子宫完成生育后还有保留的必要吗？

汪炼：在我们的传统认识里，子宫的功能几乎只和生孩子有关，而生完孩子以后，子宫就成了一个没用的废置器官，可以把它随便切除。其实，子宫对人类有重要的作用：子宫是女性重要的生殖器官，是我们每个人第一个温暖的家；子宫是女性生殖健康的重要角色，子宫是女性的尊严。有的女性切除子宫后，会觉得自己是“空腹女人”“半个女人”。据美国赫氏基金会报道，切除子宫后的女性：77.8%易怒，76.4%个性改变，66.0%丧失性欲，53.8%丧失性高潮，51.9%丧失性能力，53.3%有自杀念头，57.5%失眠，40.6%丧失母性，35.4%头痛，22.2%心悸，33.5%尿频……切除给女性带来巨大的身心伤害，甚至影响到家庭的幸福和稳定。

记者：对你们的技术我也不太懂。但恕我直言，根据我了解的情况，现在你们的这个技术似乎还没有得到医疗界的普遍认同和运用。这是为什么呢？

汪炼：你说的确实也是事实。这项技术的先进性不容置疑，推广运用也正是我们需要努力的方向。打响子宫保卫战，势在必行！这需要全社会的舆论力量唤醒更多女性对保卫子宫的重视，重拾女性的健康与自信。

为了唤起全社会对这方面的共识，今年在北京召开的全国“两会”上，全国政协委员王智彪教授已向全国政协提交提案，建议设立“世界子宫日”，呼吁全社会关注女性子宫疾病，提高女性健康意识和水平。“关爱生命，保卫子宫。”我们需要向全世界大声呐喊！

汪炼院长简介

汪炼，女，妇产科主任医师，重庆医科大学附属第一医院海扶医院院长。从事妇产科临床、科研、教学工作40余年。历任重庆市子宫良性疾病微无创治疗研究中心副主任、重庆市外阴疾病微无创治疗究中心副主任、重庆市生殖健康学会生殖医学专业委员会委员、重庆市性学会性医学专委会委员等。在《中华妇产科杂志》等国家核心期刊上发表论文20余篇。承担了《“十二五”国家科技支撑计划“超声消融子宫肌瘤的示范应用与临床再评价”项目》等多项科研项目。

王智彪教授简介

王智彪，男，妇产科学教授、博士生导师，海扶超声聚焦刀第一发明人。第10、11、12届全国政协委员。现任超声医疗国家工程研究中心主任，中国超声治疗学会主任委员、国际超声治疗学会常务理事、中国生物医学工程学会常务理事。先后承担了50余项国家自然科学基金委等重点项目。从事妇产科、超声治疗学基础和临床应用研究30年。

● 编辑：李静

The morbidity of uterine fibroids among women is 30-50%， while for those at reproductive age， it reaches up to 50%. Currently， most of the doctors will resect the uterus of the patients. In USA， About 622，000 uteruses are resected every year， and the number in China is 2，000，000. However， it was known that hysterectomy is quite harmful to women. Thus， what shall women do with uterine f broids？ Regarding this question， we had an exclusive interview with Dr. Wang Lian，Director of the world's f rst hospital specialized in the treatment of uterine f broids-the Aff liated Haifu Hospital of Chongqing Medical University.

Reporter： From the material of the hospital I reviewed， I know the core technology of your hospital is Haifu Focused Ultrasound Knife for the treatment of bone tumor， liver cancer， breast cancer，uterine f broids and etc.， which was invented by Professor W ang Zhibiao， an Obstetrician and Gynaecologist and his team. The academic name of Haifu Knife is “Model JC Focused Ultrasound Tumor Therapeutic System”， What is the relationship between "tumor" and "cancer"？

Wang Lian： Tumor can be malignant and benign， but "cancer" usually refers to the malignant tumor.

Reporter： It was heard that the patients could be treated just by one “irradiation” from your device？

Wang Lian： “Irradiation” is a kind of metaphor. The working principle of HIFU （high-Intensity Focused Ultrasound， also known as FUS or HIFUS） is similar to magni f er. As ultrasound can pass through tissues and be focused， the system focus the low intensity ultrasound and cause instant high temperature at the focus to ablate the tumor in vivo while cause no damage to tissues outside the focus. It is a treatment with no bleeding or open surgery， which is called “ultrasound ablation” in clinic.

Reporter： I have heard about Haifu Knife from news and reports more than 10 years ago， it caused a great stir around the world at that time.

Wang Lian： Yes. Professor Wang Zhibiao is a professor of obstetrics and gynecology， Doctoral advisor and the leading inventor of Haifu Knife. He devotes himself to alleviate the pain of women， and the Haifu Knife he invented can not only alleviate the pain of woman， but also patients with tumors.

Reporter： The patient will be treated just by one irradiation，this sounds like magic and unbelievable.

Wang Lian： But it is true. In 1940s， two American scientists，the Fry bothers dreamed about “focusing ultrasound in vitro to kill tumors in vivo without damage to the normal function of surrounding tissues and organs”. This dream， also a world scientif c conundrum was realized by Professor Wang Zhibiao and his team in the late 1990s here in Chongqing， China.Till now， the technology has gone global from Chongqing，with the system been applied in medical colleges and hospitals in about 20 countries and regions such as UK， Germany， Italy， Spain，Russia， South Korea， Japan. Over 20，000 cases of uterine f broids adenomyosis and more than 50，000 cases of malignant solid tumors have been treated by using HIFU， which demonstrated the successful clinical application of original innovative China high

tech.

Reporter： Really？ Unbelievable！ It sounds like myth.

Wang Lian： It is unbelievable， but it is real. More than 160 years ago， the invention of anesthetic opened the history of surgery on human； half a century ago， laparoscopy started the minimally invasive medicine. Fifteen years ago， Professor W ang Zhibiao and his team invented the focus ultrasound system，opened the door of minimally-invasive and noninvasive medicine. This is a new milestone in the world medical history.

Reporter： The focused ultrasound ablation can treat all tumors？ malignant and benign？

Wang Lian： Yes. Benign tumors include uterine fibroids，uterine adenomyosis， breast fibroma； malignant tumors include liver cancer， breast cancer， bone tumor， soft tissue sarcoma，kidney cancer， pancreas cancer and etc. All the solid tumors are suitable， no matter it is benign or malignant.

Reporter： So shall we not be so scared if we had cancer？

Wang Lian： HIFU can fight against cancer. In 1998， Xiao Xiong（a pseudonym） was diagnosed with bone tumor， she went to many large hospitals around the whole country， the answer she got from the doctors was "amputation”. At that time she was only 9 years old， just a little girl. In August 1999， haifu medical team treated her with HIFU， noninvasively. Her limb was saved and survived as a healthy girl. She went to college later， had her own career and family. We have seen many cases like this. Our hospital can treat cancers such as bone tumor， liver cancer and other cancers. Actually， we do not need to be so scared of cancer.

Reporter： Nowadays， the solutions for uterine fibroids in many hospitals are myomectomy or hysterectomy. What are the differences between HIFU and these traditional ways？

Wang Lian： The morbidity of uterine f broids among women is 30-50%， while for those at reproductive age， it reaches up to 50%.. Currently， myomectomy or hysterectomy are commonly used methods. In USA， About 622，000 uteruses are resected every year now， and the number in China is 2，000，000. Saving uterus is quite essential. As doctors， cherish life shall begin with the respect for the integrity of organs.

Patients with uterine fibroids who went through operation in traditional hospitals need to stay at hospital for about 1 week，and rest for 1～2 months for recovery. In our hospital， about 70% of our patients have the chance for non-invasive HIFU treatment. As there is no cut， the recovery time is short， about 1-2 day hospitalization and then rest for 2 days at home. The patient can also choose outpatient “day-treatment” which requires no hospitalization. We have some patients from other provinces got treatment here and the next day they went for one-day-tour in Chongqing.

Reporter： So easy？ What we knew was that women felt so cared if they are diagnosed with uterine fibroids， some even regard it as fatal disease. We never thought it could be so easy in your hospital.

Wang Lian： Uterine f broid is the most common benign tumor in women， the morbidity of women at childbearing age can reach to 50%， the malignancy probability is very low.

Reporter： Any typical case？

Wang Lian： A lot. As I have mentioned， we have treated more than 20，000 cases of dif ferent benign tumors around the world，patients are from China and abroad， most patients from abroad are attracted by the fame of HIFU technology. In 2009， "Memory in Water" （nickname）， an Australian Chinese was diagnosed with multiple uterine fibroids and the largest one was 7.6 cm in diameter. The fibroid kept growing and by early 201 1， it have grown to 11.5 cm. In Australia， lots of doctors suggested her to receive hysterectomy， once for all； however， she determined to save the uterus. In April， 2011， "Memory in W ater" learned about noninvasive ultrasound ablation of uterine f broids from the website named“savewomb”. In September 201 1， she flew from Australia to Chongqing and underwent ultrasound ablation therapy in our hospital. Doctors ablated her 15 f broids successful. Three months after HIFU， "Memory in W ater" had B-mode ultrasound scanning for follow-up in Australia， the results showed that the biggest f broid have reduced from 1 1.50 cm to 3.9 cm （shrinkage rate is 70%）， and other symptoms also got obvious relieved. Thefollow-up results shocked the Australian doctors. For more information， you can review our website （www.haifuhospital. com）.

Reporter： Now， more and more women lost their uteruses for uterine fibroids， is it necessary for women to keep the uterus after having babies？

Wang Lian： Traditionally， the uterus function seems to be child-bearing， after that， uterus could be useless organ which can be removed randomly. Actually， the uterus is an important reproductive organ for women， the first house of every human being. It plays an important role in health system which stands for woman dignity. Some women without uterus feel so hollow inside. According to American HERS foundation， among women lost uteruses， 77.8% suffer from irritability， 76.4% suffer from personality change，66.0% lose their sexual desire， 53.8% lose orgasm， 51.9% lose sexual ability， 53.3% have suicidal thoughts， 57.5% suffer from insomnia， 40.6% lose their maternal， 35.4% suffer from headache， 22.2% suf fer from heart palpitations，33.5% suffer from frequent micturition…Removal of uterus does enormous physical and psychological harm to the female， and even affect the family's happiness and stability.

Reporter： I am not so familiar with your technology. To be frank， HIFU seems to have not been generally recognized and applied in the medical f eld. Why？

Wang Lian： What you mentioned is a matter of fact. There is no doubt about the technology's advancement. Promotion is what we need to work on. Protecting the uterus is imperative. This requires the power of public opinion of the whole society to awaken more women to realize the importance of saving the uterus， regain the women's health and conf dence.

To arouse the whole society， in People's Congress & The Chinese People's Political Consultative Conference held in Beijing this year， the CPPCC National Committee，Professor Wang Zhibiao has submitted a proposal to the CPPCC proposed "world uterus day"， for the purpose of making the whole society to pay attention to female uterus disease and improve women's health consciousness and level. "Caring life， saving uterus"， we need shout loudly to the world！

Director Wang Lian's brief introduction

Wang Lian， female， obstetrics and gynecology， director of the physician， the f rst aff liated hospital of the af filiated Haifu Hospital of Chongqing Medical University；engaged in the obstetrics and gynecology clinical work， scientific research and education for more than 40 years. She is the deputy director of the Research Center of Minimally-invasive and Noninvasive Treatment for Uterine Benign Disease & the Research Center of Minimally-invasive and Noninvasive Treatment for Uterine Genital Disease， deputy director of Chongqing Institute of Reproductive Health Reproductive Medicine Professional Committee， member of Sexologist society and sexual medicine in Chongqing branch， etc. She published more than 20 academic papers in the Chinese Journal of Obstetrics and Gynecology and other core journals. She undertakes many research projects， such as the "twelfth five-year" national science and technology supporting plan "Ultrasound Ablation Uterine Fibroids Demonstration Application and Clinical Evaluation Project " and etc.

Professor Wang Zhibiao's brief introduction

Wang Zhibiao， male，professor， he is doctoral supervisor of obstetrics and gynecology， the first inventor of HIFU therapeutic system，the member of 10， 1 1， 12 session of the CPPCC National Committee. Currently， as director of the National Engineering Research Center Of Ultrasound Medicine， director of the institute committee，executive director of the International Society For Therapeutic Ultrasound， executive director of the Biomedical Engineering Society Of China； and he has successively undertaken more than 50 projects of National Natural Science Foundation and other key projects； engaged in gynecology and obstetrics，ultrasound therapeutic basics and clinical application research for 30 years.

The morbidity of uterine f broids among women is 30-50%， while for those at reproductive age， it reaches up to 50%. Hysterectomy is a therapy quite harmful to women.Exclusive Interview with Dr. Wang Lian， Director of Chongqing Haifu Hospital“The Preservation of uterus shall has no borders！”