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[摘要] 目的 评价人工泪液治疗白内障术后干眼症的临床效果。 方法 选择2011年5月～2013年5月于本院就诊的350例白内障术后干眼症患者，随机分为试验组和对照组各175例，两组患者均采用超声乳化白内障吸除术治疗白内障，术后对照组给予常规治疗，试验组在常规治疗的基础上加用人工泪液，记录两组治疗前后的泪液分泌检查（SIT）、角膜荧光素染色检查（FL）、泪膜破裂时间检查（BUT）水平及临床疗效，观察用药期间患者的不良反应情况。 结果 治疗前两组患者的SIT、FL、BUT水平差异无统计学意义（P>0.05），治疗后SIT、FL、BUT水平均显著改善，与治疗前比较，差异有统计学意义（P<0.05），且治疗后试验组的SIT、FL、BUT改善水平均优于对照组，差异有统计学意义（P<0.05）；试验组的总有效率（93.1%）显著高于对照组（79.4%），差异有统计学意义（χ2=13.9073，P=0.0002）；两组患者用药期间未发现明显不良反应情况。 结论 人工泪液治疗白内障术后干眼症，效果显著，适合临床推广应用。

[关键词] 人工泪液；白内障术后；干眼症

[中图分类号] R777 [文献标识码] A [文章编号] 1674-4721（2014）09（b）-0092-03

Effect analysis of sodium hyaluronate eye drops in the treatment of xerophthalmia after cataract surgery

XUN Hong LIAN Jin-ping

Department of Ophthalmology，Shangrao People′s Hospital in Jiangxi Province，Shangrao 334000，China

[Abstract] Objective To evaluate the curative effect of artificial tears in the treatment of xerophthalmia after cataract surgery. Methods 350 patients with xerophthalmia after cataract surgeries who visited our hospital for treatment from May 2011 to May 2013 were selected.They were evenly divided into experimental group and control group in random.Phacoemulsification for cataract was applied in both groups.After surgery，regular treatment was provided in the control group，while artificial tears was added to the experimental group on the basis of regular treatment.The levels of schirmer test （SIT），corneal fluorescein staining （FL），break-up time （BUT） before and after treatment and the clinical effect after therapy were recorded in the two groups.The adverse reactions during medication were observed. Results Before treatment，the levels of SIT，FL，and BUT had no statistical differences in the two groups （P>0.05）.After therapy，levels in these indexes all remarkably changed and indicated statistical differences compared with before treatment （P<0.05）.The improvement of these indexes after treatment in the experimental group were all superior to those in the control group，with statistical differences （P<0.05）.After therapy，the total effective rate in the experimental group was 93.1%，much higher than 79.4% in the control group，with statistical difference （χ2=13.9073，P=0.0002）.No obvious adverse reactions occurred in the two groups during medication. Conclusion Artificial tears can effectively treat patient with xerophthalmia after cataract surgery.It can obtain a remarkable clinical effect and is worthy of expansion and application in clinic.

[Key words] Artificial tears；Post-cataract surgery；Xerophthalmia

白内障是50岁以上中老年人群常见的眼科疾病[1]，是由于各种原因引起晶状体代谢紊乱，导致晶状体蛋白质变性，发生混浊，引起视物模糊。临床上针对白内障，多建议手术治疗，近几年常见的手术方法是超声乳化白内障吸除术[2]。但是白内障吸除术后初期由于泪膜破裂和泪液分泌量增加，影响泪膜的稳定性，后期很容易导致干眼症的发生。本文探讨人工泪液对白内障术后干眼症的治疗效果。

1 资料与方法

1.1 一般资料

选择2011年5月～2013年5月于本院就诊的350例白内障术后干眼症患者，将其随机分为试验组和对照组各175例。试验组中男90例，女85例，年龄55～80岁，平均（60.3±2.7）岁，病程5个月～3年，平均（11.3±4.6）个月；对照组中男91例，女84例，年龄53～78岁，平均（60.2±2.8）岁，病程5个月～3年，平均（11.2±4.8）个月；两组患者的性别、年龄、病程等一般资料比较，差异无统计学意义（P>0.05），具有可比性。