外用溃疡散和康复新液治疗复发性阿弗他溃疡疗效观察

2014-10-17董显进朱岐振

浙江医学教育 2014年2期

关键词：康复疗效

董显进，董啸，朱岐振

(玉环县人民医院，浙江玉环 317600)

外用溃疡散和康复新液治疗复发性阿弗他溃疡疗效观察

董显进，董啸，朱岐振

(玉环县人民医院，浙江玉环 317600)

目的：探讨外用溃疡散和康复新液单用与联用治疗复发性阿弗他溃疡的临床疗效。方法将120例复发性阿弗他溃疡患者按照随机数字表法分成A组、B组及C组，每组40例，A组单用外用溃疡散外涂治疗，3次/天，B组单用康复新液口服治疗，3次/天，C组给予外用溃疡散和康复新液联用治疗，疗程均为7天。比较3组患者临床疗效及平均溃疡期。结果A组与B组治疗后总有效率、平均溃疡期、疼痛指数比较差异无统计学意义(P>0.05)，C组总有效率明显优于A组及B组，平均溃疡期明显短于A组及B组，疼痛指数明显小于A组与B组(P均<0.05)。结论外用溃疡散和康复新液联用，可明显增强临床疗效，减轻疼痛，促进溃疡愈合。

外用溃疡散；康复新液；复发性阿弗他溃疡

Abstract：[Objective] To investigate the clinical efficacy of external ulcer powder and Kangfuxin fluid alone and combined to treat recurrent oral ulcer. [Method]According to the random number table method, 120 patients with recurrent oral ulcers were divided into three groups: A, B and C. Patients in group A were treated with external ulcer powder, 3 times/d and group B was treated with Kangfuxin fluid, 3 times/d, while group C received both external ulcer powder and Kangfuxin fluid, 7days/course in each group. Clinical efficacies and average ulcers ranges in three groups of patients were compared. [Result] After treatment, the total effective rate, the average period of ulcers and pain index are not statistically significant in group A and group B (P> 0.05). The total effective rate of C group is significantly better than group A and group B. Average ulcer period is significantly less than the group A and group B, pain index is significantly less than the other groups (P<0.05). [Conclusion] The combined using of external ulcer powder and Kangfuxin fluid can significantly enhance clinical efficacy, reduce pain and promote ulcer healing.

Keywords: external ulcer powder; kangfuxin fluid; recurrent oral ulcer

复发性阿弗他溃疡(Recurrent Oral Ulcer，ROU)，又称复发性口腔溃疡，是口腔内科常见疾病，发病率约为20%[1]，其病程长，常呈周期性复发，发作时创面灼痛，甚至影响患者进食。该病病因复杂，发病机制不明，目前尚无特效治疗方法。2011年3月至2013年2月，我院口腔内科采用外用溃疡散和康复新液联用治疗40例ROU，并与同期单用外用溃疡散与康复新液的同病种患者作对照研究，报告如下。