钱起龙

doi：10.3969/j.issn.1007-614x.2014.23.22

摘 要 目的：探讨肺结核住院患者并发糖尿病的临床特点与治疗方法。方法：2010年10月-2013年10月收治肺结核患者68例，回顾性分析其临床资料，通过对肺结核并发糖尿病患者与非糖尿病肺结核患者进行比较，分析并发糖尿病患者的临床特点及治疗方法。结果：肺结核并发糖尿病组表现出发热、咯血、咳嗽等症状的患者数显著多于非糖尿病肺结核组，差异具有统计学意义（P<005）；前者咳痰中结核阳性率显著高于后者，差异具有统计学意义（P<005）；前者治疗后痊愈例数显著低于后者，差异具有统计学意义（P<005）。结论：肺结核患者伴发糖尿病会加重患者的临床症状和体征，且使得结核病常规治疗效果下降，患者预后不良。

关键词 肺结核；糖尿病；临床特点

Clinical characteristics and treatment research of pulmonary tuberculosis inpatients with diabetes

Qian Qilong

Department of Tuberculosis，the Infectious Disease Hospital of Jixi City，Heilongjiang 158100

Abstract Objective：To explore the clinical characteristics and treatment methods of pulmonary tuberculosis inpatients with diabetes.Methods：68 cases with pulmonary tuberculosis were selected from October 2010 to October 2013.Their clinical data were retrospectively analyzed，and they were compared with non-diabetic patients with pulmonary tuberculosis.The clinical characteristics and treatment methods of these patients with diabetes were analyzed.Results：In the pulmonary tuberculosis patients with diabetes group，the number of patients with the fever，hemoptysis，cough symptom was more than that of the pulmonary tuberculosis patients without diabetes group，and the difference was statistically significant（P<005）.In the pulmonary tuberculosis patients with diabetes group，the tuberculosis positive rate of expectoration was significantly higher than that of the latter，and the difference was statistically significant（P<005）.The number of healing of the former after treatment was significantly lower than that of the latter，and the difference was statistically significant（P<005）.Conclusion：Diabetes can aggravate the clinical symptoms and signs of patients with pulmonary tuberculosis，and reduce the effect of conventional treatment for tuberculosis.The prognosis of patients is poor.

Key words Pulmonary tuberculosis；Diabetes；Clinical characteristics

近年来，结核发病率逐年升高，目前全球约2 000万，我国结核病患者总数仅次于印度，排在世界第二位[1]。结核分枝杆菌侵入人体之后，能在机体的细胞内迅速增殖引起局部炎性反应，同时造成局部损伤，其中肺脏是结核分枝杆菌入侵和定居的主要部位。于此同时，糖尿病患者血浆中T淋巴细胞活力下降，降低了机体对结核分枝杆菌的识别清除能力，加重了肺结核患者疾病症状[2]。2010年10月-2013年10月收治肺结核住院患者68例，回顾性分析其临床资料，探讨并发糖尿病肺结核住院患者的临床特点与治疗方法，现报告如下。

资料与方法

2010年10月-2013年10月收治肺结核住院患者68例，年龄35～69岁，平均（47.5±3.7）岁，男41例，女27例。肺结核并发糖尿病组34例，男19例，女15例；……