王占芬

[摘要] 目的 通过对高血压脑出血患者给予不同内科治疗措施，观察患者的治疗效果。 方法 选取我院2011年10月～2013年10月收治的脑出血患者56例，随机分为观察组和对照组，对照组给予常规治疗，观察组在常规治疗基础上给予依达拉奉30mg加生理盐水100mL静脉滴注，14d为1个疗程。比较治疗后两组患者的日常生活能力（ADL）以及神经功能缺损程度（NDS），并比较两组患者的临床疗效。 结果 观察组30例患者经过治疗，基本治愈12例，显著进步9例，进步6例，总有效率为90.0%，显著高于对照组80.8%（P<0.05）；观察组患者ADL、NDS评分均显著优于对照组（P<0.05）。 结论 高血压所致脑出血属于临床急症，致残率高，在临床常规基础上辅以依达拉奉治疗，可有效促进患者的神经功能康复，能够取得较好的临床疗效。

[关键词] 脑出血；内科治疗；依达拉奉

[中图分类号] R651.1 [文献标识码] B [文章编号] 2095-0616（2014）10-171-03

[Abstract] Objective To observe the treatment effects of patients with hypertensive cerebral hemorrhage through giving them different internal medicine treatment measures. Methods Fifty-six patients with cerebral hemorrhage admitted to our hospital from October 2011 to October 2013 were selected and randomly divided into the observation group and the control group.The control group was given conventional treatment and the observation group was given intravenous infusion of edaravone 30 mg plus normal saline 100mL on the basis of conventional treatment.One treatment course consisted of 14 days.The activity of daily living （ADL） and neurological function deficit （NDS） of the two groups after treatment were compared. And the clinical efficacy of the two groups was compared. Results Of the 30 patients in the observation group， after treatment，12 patients recovered basically， 9 patients improved remarkably and 6 patients improved，with the total effective rate of 90.0%， which was significantly higher than the 80.8% of the control group（P<0.05）；The observation group had significantly better ADL and NDS scores than the control group （P<0.05）. Conclusion Hypertension induced cerebral hemorrhage belongs to clinical emergency and has a high disability rate.Edaravone treatment on the basis of clinical conventional treatment can effectively promote the patients'neurological function rehabilitation and achieve preferable clinical efficacy.

[Key words] Cerebral hemorrhage；Internal medical treatment；Edaravone

脑出血是指原发性非外伤性脑实质出血，占急性脑血管疾病的20%～30%[1]。出血病因有高血压、脑血管畸形、动脉瘤等，其中高血压所致脑出血是临床最为常见的类型。高血压所致脑出血属于临床急症，致死率和致残率非常高[2]。因此，加强对脑出血患者内科治疗的研究，对于提高患者的生存率和改善患者的生活质量都具有重要意义。本研究通过对我院收治的30例高血压脑出血患者给予神经内科常规治疗，并且辅以依达拉奉注射液，取得了令人满意的临床疗效，现报道如下。

3 讨论

高血压所致脑出血是一种发病率和病死率很高的急性脑血管病。目前，临床针对脑出血的治疗原则主要是控制血压、降低颅内压、控制体温、保持水电解质平衡以及预防癫痫等支持手段。早期研究显示重组活化因子VII（rFVII）在脑出血早期应用可以有效止血，但是昂贵的价格限制了其在临床上的广泛应用。……