杨倩

[摘要] 目的 研究消化道出血患者的病因与药物治疗效果。方法 回顾性分析2010年3月～2013年3月我院收治的消化道出血患者136例的临床资料。观察及分析患者的发病原因，以及泮托拉唑钠、奥曲肽与氨甲苯酸联合治疗的临床效果。结果 136例患者的病因依次为消化性溃疡、急性胃黏膜病变、肝硬化食管静脉曲张破裂与胃癌。发病诱因为饮食不当、饮酒、药物、精神因素与劳累等因素。实施泮托拉唑钠、奥曲肽、氨甲苯酸联合治疗消化性溃疡的优良率为 95.9%，治疗急性胃黏膜病变的优良率为93.3%，治疗肝硬化食管静脉曲张破裂的优良率为90.9%，治疗胃癌的优良率为100%。结论 消化道出血疾病的病因是消化性溃疡，诱因常是口服刺激性的药物。采用泮托拉唑钠、奥曲肽、氨甲苯酸联合治疗消化道出血具有较高的应用价值，值得临床进一步推广应用。

[关键词] 消化道出血；泮托拉唑钠；奥曲肽；氨甲苯酸

[中图分类号] R573.2   [文献标识码] B   [文章编号] 2095-0616（2014）08-188-03

Experience of drug treatment in patients with gastrointestinal bleeding

YANG Qian

Tongbai People's Hospital in Henan Province,Tongbai 474750,China

[Abstract] Objective To study the etiology and clinical efficacy of drug treatment on patients with gastrointestinal hemorrhage. Methods Clinical data of 136 cases with gastrointestinal bleeding from March 2010 to March 2013 in our hospital were retrospectively analyzed.Aetiological agent and clinical efficacy of pantoprazole sodium, octreotide combined with aminomethylbenzoic acid treatment were observed and analyzed. Results The causes of 136 cases of patients were peptic ulcer, acute gastric mucosal lesion, cirrhosis esophageal varices and gastric cancer. The predisposing factors were improper diet, alcohol, drugs, mental factors and fatigue factors. The excellent and good rate of implementation of pantoprazole sodium, omeprazole, combined with aminomethylbenzoic acid for peptic ulcer was 95.9%, the excellent and good rate of treatment of acute gastric mucosal lesion was 93.3%, the excellent and good rate for liver cirrhosis with esophageal varices was 90.9%, and the excellent and good rate of gastric cancer was 100%. Conclusion The causes of hemorrhage of digestive tract diseases are peptic ulcer, predisposing factors usually are oral irritation. Omeprazole,pantoprazole sodium combined with aminomethylbenzoic acid for gastrointestinal bleeding shows a high application value, worthy of further promotion and application.

[Key words] Gastrointestinal bleeding;Pantoprazole sodium;Omeprazole;Aminomethylbenzoic acid

上消化道出血在临床上比较常见，主要症状为呕血及黑便、休克等[1]。此病发病部位很特殊，需要给予高度重视及积极配合治疗。一旦延误病情则会导致愈合效果。为研究消化道出血患者的病因与药物治疗效果，笔者回顾性分析了2010年3月～2013年3月我院收治的消化道出血患者136例的病例资料，现总结报道如下。

1 资料与方法

1.1 一般资料

选择2010年3月～2013年3月我院收治的消化道出血患者136例病例，其中男76例，女60例；年龄最小17岁，最大58岁，平均42.3岁。所有患者经过胃镜检查均确诊上消化道出血，并且只需要运用药物治疗。……