何孙香

[摘要] 目的 探究中医辨证施治辅助化疗对晚期胃癌患者的应用价值。 方法 选取本院2012年1月～2012年6月收治的86例晚期胃癌患者，随机分成观察组与对照组，各43例。观察组患者给予中医辨证施治辅助化疗进行治疗，对照组患者只行化疗治疗。 结果 观察组与对照组的总有效率分别为41.86%、32.56%，两组比较，差异有统计学意义（P<0.05）；治疗结束后，观察组患者的半年、1年存活率分别为76.74%、34.88%，对照组分别为44.19%、9.30%，两组比较，差异有统计学意义（P<0.05）。 结论 中医辨证施治辅助化疗治疗晚期胃癌能够明显提高患者对化疗的耐受力，值得临床推广应用。

[关键词] 晚期胃癌；化疗；中医辨证施治

[中图分类号] R735.2 [文献标识码] A [文章编号] 1674-4721（2014）04（a）-0124-03

[Abstract] Objective To investigate the application value of syndrome differentiation and treatment assisting chemotherapy for patients with late gastric cancer. Methods 86 patients with late gastric cancer admitted into our hospital from January 2012 to June 2012 were randomly divided into the observation group （n=43） and the control group （n=43）.In the observation group，patients were treated by syndrome differentiation and treatment of TCM assisting chemotherapy，while in the control group，patients were treated by only chemotherapy. Results The total effective rate in the observation group and the control group were 41.86%，32.56% respectively and there was a statistical difference between the two groups （P<0.05）.After the end of treatment，the survival rate of half a year and one year were 76.74%，34.88% respectively in the observation group while in the control group，the survival rate of half a year and one year were 44.19% and 9.30% respectively and there was a statistical difference between the two groups （P<0.05）. Conclusion For the treatment of late gastric cancer， syndrome differentiation and treatment of TCM assisting chemotherapy can remarkably improve patient′s tolerance to chemotherapy.It is worthy of clinical promotion and application.

[Key words] Late gastric cancer；Chemotherapy；Syndrome differentiation and treatment of TCM

胃癌是临床上常见的消化系统疾病，在我国胃癌高居恶性肿瘤首位，超过一半的患者到医院就诊就已到中晚期， 并且该病的根治性切除率较低。早期胃癌常规的治疗方法是以手术为主，适合手术的患者应尽可能地将其原发和转移病灶切除，并与放化疗、免疫治疗结合胃癌疗法相配合[1-2]。随着多种新辅助治疗理论与技术的不断完善，在术前展开辅助性化疗来保证晚期胃癌手术切除率和根治率，可有效减少术后的复发。本院将中医辨证施治联合西医化疗应用于治疗晚期胃癌，其效果确切。

1 资料与方法

1.1 一般资料

选取我院2012年1月～2012年12月收治的86例晚期胃癌患者，将其随机分成观察组与对照组，各43例。观察组：男26例，女17例，年龄50～78岁，平均（65.4±6.5）岁；对照组：男28例，女15例，年龄51～76岁，平均（64.8±6.3）岁。所有患者通过病理与CT检查确诊为胃癌晚期。其中腺癌43例，印戒细胞癌39例，腺鳞癌1例，鳞癌3例。两组患者的一般资料比较，差异无统计学意义（P>0.05），具有可比性。

1.2 治疗方法

对照组患者仅给予化疗方案进行治疗。……