[摘要] 目的：探讨疏肝健脾汤治疗功能性消化不良的临床疗效。方法：随机将我院156例消化不良患者分为两组，治疗组78例服用疏肝健脾汤，对照组78例口服雷尼替丁和吗丁啉，疗程均为4周。结果：治疗组治愈率为29.5%，总有效率为91.0%；对照组治愈率为15.4%，总有效率为75.6%。两组治愈率和总有效率比较，差异均有高度统计学意义（均P<0.01）。两组治疗后各临床症候积分均较治疗前有明显改善（均P<0.05）；治疗组治疗后的腹胀、烧心、恶心症状症候评分与对照组比较，差异均有统计学意义（均P<0.05）。结论：疏肝健脾汤对功能性消化不良的临床治疗效果较好，且副作用小。

[关键词] 功能性消化不良；中医疗法；疏肝；健脾

[中图分类号] R259.744 [文献标识码] A[文章编号]1673-7210（2011）11（c）-117-02

Observation of efficacy on Soothing Liver and Strengthening Spleen Decoction in the treatment of 78 patients with functional dyspepsia

MO Luli

Guangzhou Dongsheng Hospital, Guangdong Province, Guangzhou 510120, China

[Abstract] Objective: To investigate the clinical efficacy on Soothing Liver and Strengthening Spleen Decoction in the treatment of functional dyspepsia. Methods: 156 patients were randomly divided into treatment group and control group. The 78 patients of the treatment group received Soothing Liver and Strengthening Spleen Decoction while the 78 patients of the control group received Ranitidine and Domperidone. The courses of treatment for two groups were 4 weeks. Results: For the treatment group, the cure rate was 29.5% and the total effective rate was 91.0%. For the control group, the cure rate was 15.4% and the total effective rate was 75.6%. There were significant differences of the cure rate and the total effective rate between the two groups (all P<0.01). The points of clinical symptoms were significantly improved in the treatment group after treatment compared with before treatment (all P<0.05). The points of abdominal distension, heartburn, nausea in the treatment group compared the control group, there were significant differences (all P<0.05). Conclusion: Soothing Liver and Strengthening Spleen Decoction in the treatment of functional dyspepsia has better clinical effects and fewer side effects.

[Key words] Functional dyspepsia; Chinese medical therapy; Soothing liver; Strengthening Spleen

功能性消化不良（functional dyspepsia，FD）是临床上常见的一种功能性胃肠病，是指具有上腹痛、腹胀、早饱、嗳气、食欲不振、恶心、呕吐等上腹不适症状，临床上各个症状可单独或混合出现，是经检查排除引起这些症状的器质性疾病的一组临床综合征。2005~2010年笔者应用疏肝健脾汤治疗功能性消化不良，疗效满意，现报道如下：

1 资料与方法

1.1 一般资料

选取我院消化不良患者156例，将其随机分为两组。治疗组78例，男35例，女43例；年龄18~69岁，平均38.5岁；病程0.3~3.0年。对照组78例， 男32例，女46例，年龄19~68岁，平均37.5岁；病程0.3~2.8年。全部患者均无出血、穿孔、梗死等并发症。两组患者性别、年龄、病程等方面比较，差异无统计学意义（P>0.05），具有可比性。

1.2 诊断标准

参照《内科学》相关规定拟定[1]：①上腹痛、腹胀、早饱、嗳气、反酸、恶心、呕吐等上腹部症状超过4周；②内镜检查未发现溃疡、肿瘤等器质性病变，亦未发现食管炎，也无相关病史；③实验室、B 超、X线等检查排除肝、胆、胰及肠道器质性疾病；④无糖尿病、结缔组织病及神经肌肉等全身性疾病；⑤无腹部手术史。

1.3 方法

治疗组服用自拟中药方剂疏肝健脾汤，处方：郁金10 g、佛手10 g、合欢花10 g、白芍15 g、茯苓15 g、党参15 g、木香6 g、莱菔子10 g、白术15 g、砂仁8 g、黄连4 g、甘草6 g。……