18例介入手术治疗输卵管异位妊娠的临床分析
2011-11-17崔月清陈亚奇李兴海
崔月清 陈亚奇 李兴海
基金项目:2007年盐城市医学科技发展计划项目(YK2007156)
作者单位:224001 东南大学医学院附属医院盐城市第三人民医院
通讯作者:崔月清
【摘要】 目的 探讨经双侧子宫动脉灌注甲氨蝶呤及介入栓塞治疗输卵管妊娠的临床应用。方法 分析18例输卵管妊娠患者行双侧子宫动脉造影,甲氨蝶呤灌注栓塞对治疗前后患者的血β-hCG下降,B超检查及术后4个月子宫输卵管碘油造影检查(HSG)输卵管通畅率作为治疗效果的评价手段。结果 18例患者中17例患者治疗后复查B超提示胚胎缩小,β-hCG明显下降,阴道出血减少或中止,1例患者胚胎继续生长有内出血情况转手术治疗。4个月后17例患者行子宫输卵管碘油造影,15例通畅,通畅率83.3%。结论 双侧子宫动脉灌注甲氨蝶呤化疗及介入栓塞术治疗输卵管妊娠是一种损伤小、疗效佳的治疗技术,是保守治疗输卵管妊娠的有效方法。
【关键词】 介入性; 输卵管妊娠; 甲氨蝶呤; 子宫动脉栓塞术
Surgical treatment of 18 patients involved in clinical analysis of tubal ectopic pregnancy CUI Yue-qing,CHEN Ya-qi,LI Xing-hai.The Third People's Hospital of Yancheng, Yancheng 224000,China
【Abstract】 Objective To evaluate methotrexate and bilateral uterine artery embolization treatment of tubal pregnancy in the clinical application.Methods 18 patients with tubal pregnancy were treated with uterine artery angiography, embolization perfusion before and after treatment with methotrexate in patients with decreased serum β-hCG,B-ultrasound and 4 months after hysterosalpingography examination (HSG) Tubal patency rate as the evaluation of treatment means.Results In 18 patients,17 patients were reviewed after treatment,B-prompt reduce embryo, β-hCG decreased significantly reduce or stop bleeding,a case of bleeding in patients with conditions the growth of embryos to transfer surgery.4 months in 17 patients underwent hysterosalpingography, 15 cases of patency, patency rate of 83.3%.Conclusion Bilateral uterine artery methotrexate chemotherapy and embolization in the treatment of tubal pregnancy is a little damage,excellent efficacy of therapy was an effective conservative treatment method for tubal pregnancy.
【Key words】 Interventional; Tubal pregnancy; Methotrexate; Emboliation of uterine arterty
异位妊娠是妇科常见的急腹症之一,以输卵管妊娠最常见,约占95%[1]。输卵管黏膜炎及输卵管周围炎是异位妊娠的主要原因。由于年轻未婚、未育女性在异位妊娠患者中所占比例升高,多数患者寻找一种创伤小,保留生育功能的治疗方法。笔者所在医院2006年1月~2009年12月的18例输卵管患者行子宫动脉灌注甲氨蝶呤及介入栓塞治疗,取得良好的治疗效果,现报道如下。
1 资料和方法
1.1 一般资料 2006年1月~2009年12月根据临床症状,血β-hCG,超声确诊的18例输卵管妊娠的患者有生育要求并愿意接受随访者行介入治疗。……
