无痛人工流产术中配合应用米索前列醇220例临床观察

2011-09-26王松珍

中国民族民间医药 2011年5期

关键词：手术

王松珍

河南省洛阳市瀍河区妇幼保健中心，河南洛阳 471002

无痛人工流产术中配合应用米索前列醇220例临床观察

王松珍

河南省洛阳市瀍河区妇幼保健中心，河南洛阳 471002

为观察米索前列醇在无痛人工流产术中的应用效果，将220例自愿要求终止妊娠者随机分为观察组和对照组各110例，观察组术前半小时舌下含服米索前列醇400ug，对照组术前不使用任何促宫颈成熟的药物，观察两组宫颈扩张情况、术中出血量、手术时间及麻醉药用量情况。观察组显效率和总有效率为84%和100%，分别高于对照组51.8%和93.7%，差异有统计学意义 (p＜0.05)。观察组术中出血量和加用异丙酚发生率均低于对照组，差异均有统计学意义 (p＜0.05)。无痛人工流产术前舌下含服米索前列醇，可使宫颈明显松弛，子宫收缩，且无明显药物不良反应，安全有效，简便易行，值得推广应用。

米索前列醇;无痛人工流产术;临床观察

Abstract：In order to observe the effect of the indolent artificial abortion operation with the application of Misoprostol，220 cases with unbidden gestation termination were randomly divided into two equal groups，which were respectively called observation group and comparison group．The members in the observation group were required to take sublingual Misoprostol of 400ug half hour before operation and the ones in the comparison group were not required to take any medicine for cervical ripening．The cervical dilation，blood loss during operation，operation duration and narcotic dosage were observed for the two groups．The effective rate and total effective rate of observation group were 84%and 100%，which were respectively 51．8%and 93．7%higher than the ones of comparison group with significance in statistics(p＜0．05)．The blood loss and the additional usage rate of Propofol for observation group were lower than comparison group with significance in statistics(p＜0．05)．Sublingual Misoprostol before indolent artificial abortion operation can obviously promote cervical dilation and uterus contraction without medicine adverse reaction．The method is worth popularizing due to its safety，effectiveness and simplification．

Key words：Misoprostol;Indolent artificial abortion;Clinical observation

人工流产是目前广泛应用于避孕失败或者从优生优育角度不宜继续妊娠的一种补救措施之一。传统的人工流产手术痛苦大、并发症多，随着生活水平和医疗水平的提高，无痛人工流产手术逐渐被人们接受，但无痛人工流产术中使用的麻醉药异丙酚无直接使宫颈软化和松弛的作用，而宫颈的紧张度对手术操作非常重要。我院2008年1月—2010年6月对220例要求无痛人工流产终止妊娠的妇女，术前30分钟舌下含服米索前列醇，取得良好效果，现报道如下。