易晓明 彭小娜

摘要：目的  探討氧气驱动雾化吸入对支气管哮喘患者肺功能及血氧饱和度的影响。方法  选取2017年3月～2019年3月我院收治的86例支气管哮喘患者，按照随机数字表法分为对照组和观察组，各43例。对照组实施超声雾化吸入治疗，观察组实施氧气驱动雾化吸入治疗，比较两组肺功能指标（PA-aDO2、FEV1、PEF及RI）、血氧饱和度及不良反应发生率。结果  治疗后，观察组PA-aDO2、RI低于对照组[（2.40±0.39）kPa vs（2.97±0.42）kPa]、[（0.18±0.08）vs（0.29±0.06）]，FEV1、PEF高于对照组[（2.01±0.16）L vs（1.46±0.18）L]、[（125.29±9.68）ml/min vs（108.55±8.79）ml/min]，差异有统计学意义（P<0.05）。观察组血氧饱和度高于对照组[（95.04±2.53）% vs（88.63±2.42）%]，差异有统计学意义（P<0.05）。两组不良反应发生率比较（6.98% vs 11.63%），差异无统计学意义（P>0.05）。结论  氧气驱动雾化吸入可有效增强支气管哮喘患者肺功能，提高血氧饱和度，且不增加不良反应。

关键词：支气管哮喘;氧气驱动雾化吸入;肺功能;血氧饱和度

中图分类号：R725.6                                 文献标识码：A                                 DOI：10.3969/j.issn.1006-1959.2019.23.030

文章编号：1006-1959（2019）23-0110-03

Effect of Oxygen-Driven Aerosol Inhalation on Lung Function and

Oxygen Saturation in Patients with Bronchial Asthma

YI Xiao-ming1，PENG Xiao-na2

（Department of Internal Medicine，Subject Two1，Department of Respiratory Medicine2，the Second People's Hospital of Yichun City，Yichun 336000，Jiangxi，China）

Abstract：Objective  To investigate the effects of oxygen-driven aerosol inhalation on lung function and oxygen saturation in patients with bronchial asthma. Methods  86 patients with bronchial asthma admitted to our hospital from March 2017 to March 2019 were randomly divided into the control group and the observation group， 43 cases each. Ultrasonic nebulization inhalation was performed in the control group， and oxygen-driven nebulization inhalation was performed in the observation group. The lung function indexes （PA-aDO2， FEV1， PEF and RI）， blood oxygen saturation and adverse reaction rate were compared between the two groups.Results  After treatment， the observation group PA-aDO2， RI was lower than the control group [（2.40±0.39） kPa vs （2.97±0.42） kPa]， [（0.18±0.08） vs （0.29±0.06）]， FEV1， PEF was higher than the control group [（2.01±0.16） L vs （1.46±0.18） L]， [（125.29±9.68） ml/min vs （108.55±8.79） ml/min]， the difference was statistically significant （P<0.05）. The oxygen saturation of the observation group was higher than that of the control group [（95.04±2.53）% vs （88.63±2.42）%]， the difference was statistically significant （P<0.05）. The incidence of adverse reactions was compared between the two groups （6.98% vs 11.63%），the difference was not statistically significant （P>0.05）.Conclusion  Oxygen-driven aerosol inhalation can effectively enhance lung function and improve oxygen saturation in patients with bronchial asthma without increasing adverse reactions.