AProspective Studyon the Combined Application ofJin Sanzhenand Cognitive Training in the Early Rehabilitation Treatment ofCognitive Impairment after Stroke/LI Pingyuan， YUAN Tengfei， WEIWen， LIUShan，LI Huijun.//Medical Innovation of China， 2025，22（16）： 018-021

[Abstract]Objective：Toanalyzetheapplication effectof the combination of Jin Sanzhen and cognitive trainingintheearly rehabilitationtreatmentof post-strokecognitive impairment （PSCI）.Method：Atotal of 103 patients with PSCI who were treated in the Department of Traditional Chinese Medicine and the Department of Rehabilitation Medicine of Guangdong Provincial People's Hospital Ganzhou Hospital from December 2022 to July 2024 were selected.The patients were randomly divided into a control group （n=5O）and a treatment group （ n =53）based on the random number table method.Both groups received basic treatment.On this basis，the control group received cognitive training，while the treatment group received Jin Sanzhen combined cognitive training. The application efects of the two groups of different intervention programs were compared.Result： After 4 weeks of treatment （T）and8 weeks of treatment （T2），the scores of mini-mental state examination （MMSE）， activities of daily living （ADL）， montreal cognitive assessment （MoCA），and Fugl-Meyer assessment scale （FMA） inthe treatment group were higher than those in the control group，the diferences were statisticallysignificant （ P lt;0.05）. Conclusion： The implementation of Jin Sanzhen and cognitive training combined intervention in early rehabilitation treatment of PSCI patients can sustainably improve their cognitive function and enhance their selfcare ability.

[Key Words] Post-stroke cognitive impairmentEarly rehabilitation treatmentJin Sanzhen Cognitive training

First-author'saddres： Department of Traditional Chinese Medicine，Guangdong Provincial People's Hospital Ganzhou Hospital，Ganzhou 341ooo， China

脑卒中是一种临床较为常见的急性脑血管疾病，发病群体以中老年人为主，具备高致残率、高致死率等特点[1-2]。随着病情不断进展，大多数患者可出现不同程度的认知功能障碍（如视觉空间障碍等），倘若未接受科学、有效的治疗干预，可能会加大痴呆等不良情况的发生风险[3-4]。临床主要采取药物、针刺等方式治疗卒中后认知功能障碍（post-stroke cognitve function impairment，PSCI），可抑制疾病进展，但是单一治疗无法逆转病情，临床应用受限。认知训练通过开展强度适宜的、重复性的认知功能训练活动，持续对脑部细胞加以刺激，推动突触的增长，加快受损神经细胞的修复速度，使得神经纤维得以重新构建，有利于调整神经功能、改善认知功能[5-7]。靳三针是由靳瑞教授所创立的，在健忘、痴呆等疾病治疗中效果显著。鉴于此，本文通过多中心前瞻性临床研究与分析靳三针、认知训练联合在卒中后认知障碍（PSCI）早期康复治疗中的应用效果，旨在为临床提供一定借鉴，现报道如下。

1资料与方法

1.1一般资料

以2022年12月—2024年7月广东省人民医院赣州医院中医科和康复医学科治疗的103例PSCI患者为主要研究对象。纳入标准：影像学、症状表现等综合确诊为脑卒中，与临床诊断标准相符合;发病后各项体征稳定；卒中后精神状态简易量表（mini-mental stateexamination，MMSE）评分 lt;27 分；年龄40＼～75岁；文化水平在小学以上；病程时间lt;6 个月。排除标准：意识、视听、理解等功能障碍；患有其他可能导致认知障碍的疾病（血管性认知障碍）；中重度抑郁；肝肾功能异常、充血性心衰、呼衰、恶性肿瘤；……