田晓双 代玲

【摘要】目的：分析宫腔镜下子宫内膜息肉电切除术对比子宫内膜息肉摘除加电凝术治疗子宫内膜息肉对血管内皮生长因子（VEGF）水平的影响。方法：对2019年3月—2020年12月该段时间入院的子宫内膜息肉患者78例展开分组研究，对照组实施子宫内膜息肉摘除加电凝术治疗，观察组实施宫腔镜下子宫内膜息肉电切除术治疗，对比两组治疗前后月经量、血红蛋白含量及血管内皮生长因子变化情况。结果：两组治疗前月经量、血红蛋白含量及血管内皮生长因子比较无差异（P>0.05）；治疗6个月后观察组月经量、血管内皮生长因子水平低于对照组，血红蛋白含量高于对照组（P<0.05）；观察组复发率为5.1%低于对照组的25.6%（P<0.05）。结论：与子宫内膜息肉摘除加电凝术治疗相比，宫腔镜下子宫内膜息肉电切除术效果更佳，能有效减少月经量，提高患者机体血红蛋白含量，降低血管内皮生长因子的表达，减少复发，具有较高应用价值。

【关键词】子宫内膜息肉；宫腔镜；电切除术；摘除加电凝术

The effect of hysteroscopic electric resection of endometrial polyps compared with endometrial polyp removal plus electrocoagulation on the level of VEGF factor

TIAN Xiaoshuang， DAI Ling

Peoples Hospital of Yuancheng District， Heyuan City， Guangdong Province， Heyuan， Guangdong 517000， China

【Abstract】Objective： To analyze the effect of hysteroscopic electric resection of endometrial polyps compared with endometrial polyp removal plus electrocoagulation on the level of vascular endothelial growth factor （VEGF）. Methods： A group study of 78 endometrial polyp patients admitted to the hospital from March 2019 to December 2020 was carried out. The control group received endometrial polyp removal and electrocoagulation treatment， and the observation group received hysteroscopic uterine surgery. Electric resection of endometrial polyps was performed， and the changes in menstrual volume， hemoglobin content and vascular endothelial growth factor were compared between the two groups before and after treatment. Results： There was no difference in menstrual volume， hemoglobin content and vascular endothelial growth factor between the two groups before treatment（P>0.05）； after 6 months of treatment， the menstrual volume and vascular endothelial growth factor levels of the observation group were lower than those of the control group， and the hemoglobin content was higher than that of the control group Group （P<0.05）； the recurrence rate of the observation group was 5.1% lower than that of the control group 25.6%（P<0.05）. Conclusion： Compared with the treatment of endometrial polyp removal and electrocoagulation， the effect of hysteroscopic endometrial polypectomy is better， which can effectively reduce menstrual volume， increase the patients body hemoglobin content， and reduce the expression of vascular endothelial growth factor ， Reduce recurrence， and have high application value.

【Key？Words】Endometrial polyps； Hysteroscopy； Electrical resection； Removal and electrocoagulation

臨床对于子宫内膜息肉多以手术治疗为主，随着宫腔镜技术的发展和完善，在临床的应用也愈加广泛，具有视野清晰、安全、方便的优势，与传统刮宫术相比，对患者造成的创伤更小。但宫腔镜下不同方式切除其疗效也存在一定差异[1]。因此研究采用宫腔镜下电切术与摘除术加电凝2种方式治疗该病，并对其治疗效果，现将其汇报如下。

1 资料与方法

1.1 一般资料

对2019年3月—2020年12月该段时间入院的子宫内膜息肉患者78例展开分组研究，经B超病理学检查等明确诊断，排除子宫肌瘤、子宫内膜癌、肝肾功能存在严重器质性疾病者。观察组39例，年龄22～46岁，平均年龄（33.5±3.2）岁，病程1～3年，平均病程（2.5±1.2）年，其中单发息肉者22例，多发息肉者17例；对照组39例，年龄22～49岁，平均年龄（32.5±3.5）岁，病程1～4年，平均病程（2.6±1.3）年，其中单发息肉者25例，多发息肉者14例。两组……