林青青

【摘 要】 目的：觀察四神丸汤剂加减应用于小儿脾肾阳虚型泄泻的临床效果。方法：选取61例脾肾阳虚型泄泻患儿，随机分为对照组30例，予蒙脱石散口服治疗;观察组31例，予四神丸汤剂口服治疗，不与其他治疗方法联用。疗程5 d，对治疗前后症状评分和总有效率进行比较。结果：对照组治疗后症状总评分显著高于观察组，而总有效率明显低于观察组，且差异有统计学意义（P<0.05）。结论：四神丸汤剂加减对小儿脾肾阳虚型泄泻疗效显著，值得临床推广。

【关键词】 四神丸;小儿泄泻;脾肾阳虚型

【中图分类号】R256.34 【文献标志码】 A【文章编号】1007-8517（2022）14-0110-04

Observation on the Clinical Effect of Sishen Pill Decoction in Treating Diarrhea of Spleen-Kidney-Yang Deficiency in Children

LIN Qingqing

Quanzhou Traditional Chinese Medicine Hospital， Quanzhou 362000，China

Abstract：Objective To investigate the clinical effect of sishen Pill decoction on diarrhea of spleen-kidney-yang deficiency in children. Methods Sixty-one children with diarrhea of spleen-kidney-yang deficiency were randomly divided into control group （n=30） and observation group （n=31）. The symptom score and total response rate were compared before and after treatment for 5 days. Results The total symptom score of control group was significantly higher than that of observation group， and the total effective rate was significantly lower than that of observation group， and the difference was statistically significant （P<0.05）. Conclusion Sishen pill decoction has significant curative effect on diarrhea of spleen-kidney-yang deficiency in children， which is worth popularizing.

Key words：Sishen Pill; Diarrhea in Children; Deficiency of Spleen and Kidney Yang

小儿腹泻为儿科多发病，临床以便次增多、粪质稀薄或稀如水样为主要表现，可伴见食欲不振、面色萎黄等兼症，又被称作“泄泻”，在2岁以下的儿童群体中具有较高的发病率^[1]。该病常因伤于乳食、外邪袭扰或脾肾阳气亏虚等，使得肠道泌别清浊功能失常，内容物混杂而下。腹泻若急性发作，多为感染导致，临床常规予补液纠正酸碱平衡及电解质紊乱后常可减轻;但仍有部分患儿易转为迁延性、慢性腹泻而反复不愈，不但给患儿家庭带来困扰，还会导致营养不良、发育迟缓等弊病^[2]。这部分慢性腹泻患儿的中医主要证型常以脾虚泻以及脾肾阳虚泻两种为主。笔者在临床上对于脾肾阳虚型泄泻患儿，应用四神丸汤剂加减进行治疗，取得满意的临床效果，现总结如下。

1 临床资料

1.1 一般资料 根据随机数字表法，将2020年1月至2020年12月间经泉州市中医院儿科门诊治疗年龄处于6个月至5岁之间的61例脾肾阳虚型泄泻患儿分为对照组（30例）和观察组（31例）。……