细胞块结合免疫组化技术在恶性胸腔积液病理诊断中的应用价值
2021-09-10常伟建
常伟建

摘要:目的 探讨细胞块结合免疫组化技术在恶性胸腔积液病理诊断中的应用效果。方法 将50例于2020年3月-2021年3月收治的恶性胸腔积液患者纳入研究,均进行细胞块免疫组化检查,并与综合诊断结果进行对比,以评估细胞块结合免疫组化技术的应用价值。结果 细胞块结合免疫组化技术诊断准确率为96%,与综合诊断相对比不具有统计学意义(P>0.05)。结论 恶性胸腔积液病理诊断应用细胞块结合免疫组化技术具有较高诊断准确率,可为临床治疗提供有效参考,值得被应用。
关键词:细胞块;免疫组化技术;恶性胸腔积液;病理诊断
[Abstract]Objective To explore the application effect of cell block combined with immunohistochemistry in the pathological diagnosis of malignant pleural effusion. Methods 50 cases of malignant pleural effusion patients from March 2020 to March 2021 were included in the study,all of them were examined by cell block immunohistochemistry,and compared with the comprehensive diagnosis results,in order to evaluate the application value of cell block combined with immunohistochemistry. Results the diagnostic accuracy of cell block combined with immunohistochemistry was 96%,which was not statistically significant compared with comprehensive diagnosis(P > 0.05). Conclusion the application of cell block combined with immunohistochemistry in the pathological diagnosis of malignant pleural effusion has a high diagnostic accuracy,which can provide an effective reference for clinical treatment and is worthy of application.
[Key words]cell mass;Immunohistochemical technique;Malignant pleural effusion;pathologic diagnosis
正常情况下人体会有10-20ml的液体从胸壁溢出,再从胸壁小管回吸,并始终保持平衡,以在胸腔里起润滑作用。该种现象无论做胸部CT还是胸腔彩超,是都看不见胸腔积液的。但是当发生病变后,会有胸腔积液的产生,并通过可影像学检查进行观察。而恶性胸腔积液是恶性病变,少部分是原发于胸膜的病变,多见于肺癌胸膜转移【1】。对于恶性胸腔积液,通常要引流胸水或者穿刺胸水,找到癌细胞后才能确诊是恶性胸腔积液,然后在展开针对性治疗。而本次纳入研究恶性胸腔积液患者50例,并于2020年3月-2021年3月开展医学研究,着重分析细胞块结合免疫组化技术的应用效果。现将详细内容进行如下报告:
1 资料和方法
1.1一般资料
经院内伦理委员会批准,将50例于2020年3月-2021年3月收治的恶性胸腔积液患者纳入研究,均进行细胞块免疫组化检查,且均签署知情文件。……
