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纳洛酮及丙种球蛋白治疗小儿重症病毒性脑炎的效果评价

2021-09-10杨洪

智慧医学 2021年2期

杨洪

摘要:目的 纳洛酮及丙种球蛋白治疗小儿重症病毒性脑炎的效果评价。方法 回顾性抽取在我院进行治疗的重症病毒性脑炎患儿60例,日期2018年9月-2019年9月,依据随机分组的原则分为参照组与观察组,各30例。参照组开展常规治疗,观察组开展纳洛酮及丙种球蛋白治疗,对比两组临床效果、症状缓解时间。结果 观察组在临床效果、症状缓解时间的对比上有差异,均明显优于参照组,差异显著(P<0.05)。结论 在患儿的治疗中应用纳洛酮及丙种球蛋白治疗,可保证临床效果,促进患儿症状缓解,值得进一步推广。

关键词:纳洛酮;丙种球蛋白;小儿重症病毒性脑炎;临床效果

[Abstract]Objective To evaluate the efficacy of naloxone and gamma globulin in the treatment of severe viral encephalitis in children. Methods 60 children with severe viral encephalitis treated in our hospital were selected retrospectively from September 2018 to September 2019. According to the principle of random grouping,they were divided into control group and observation group,30 cases in each group. The control group received routine treatment,and the observation group received naloxone and gamma globulin treatment. The clinical effect and symptom relief time of the two groups were compared. Results the clinical effect and symptom relief time of the observation group were significantly better than those of the control group(P < 0.05). Conclusion the application of naloxone and gamma globulin in the treatment of children can ensure the clinical effect and promote the remission of symptoms,which is worthy of further promotion.

[Key words]naloxone;gamma globulin;severe viral encephalitis in children;clinical effect

小儿病毒性脑炎是因病毒感染所导致的一种脑实质病变,此病于临床较为常见【1】。其中,重症病毒性脑炎则更为凶险,其具有较高的致残率、病死率,许多重症患儿多在治疗后遗留神经系统后遗症。时至今日,临床在对患儿进行治疗时,主要应用的便是常规抗病毒治疗的方法,并辅以其他药物治疗的方法【2】。正是这样的情况下,纳洛酮及丙种球蛋白治疗是否能够取得相应的效果,则得到临床广泛关注。基于此,本次实验将围绕着纳洛酮及丙种球蛋白治疗小儿重症病毒性脑炎的效果进行论述,详细报道如下:

1 资料和方法

1.1 一般资料

回顾性抽取在我院进行治疗的重症病毒性脑炎患儿60例,日期2018年9月-2019年9月,依据随机分组的原则分为参照组与观察组,各30例。参照组男18例,女12例,年龄3-11岁,平均年龄(5.03±1.14)岁;观察组男19例,女11例,患者年龄为3-12岁,平均年龄(5.48±1.26)岁;两组的一般资料,无显著差异(P>0.05)。……

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