应洁敏 范娟 杨飙 黄俊 邬小龙

摘要 目的：探究康婦消炎栓对子宫肌瘤术后患者血清C反应蛋白（CRP）、白细胞计数（WBC）水平及肠胃功能恢复的影响。方法：选取2017年1月至2017年11月马鞍山市中心医院收治的子宫肌瘤患者80例作为研究对象，按照随机数字表法分为对照组和观察组，每组40例。对照组给予术后常规预防性抗炎，观察组在此基础上给予康妇消炎栓塞肛治疗，比较2组患者治疗效果、麻醉时间、手术时间、CRP、WBC及肠胃功能恢复情况，如术后首次排气时间、术后首次排便时间等。结果：治疗后，2组患者CRP、WBC水平较治疗前降低，而且观察组CRP、WBC水平较对照组低（P<0.05）。2组手术时间及麻醉时间比较，差异无统计学意义（P>0.05），观察组术后首次排气时间、术后首次排便时间与对照组比较差异有统计学意义（P=0.002、0.008<0.05）。观察组治疗有效率95.00%，对照组为77.50%，差异有统计学意义（P<0.05）。结论：康妇消炎栓应用于子宫肌瘤术后患者，能够降低术后炎症反应，促进术后肠胃功能恢复，值得推广。

关键词 康妇消炎栓;子宫肌瘤术后;C反应蛋白;白细胞;肠胃功能恢复;炎症反应;腹胀;疗效

Effects of Kangfu Xiaoyan Suppositories on Serum Levels and Gastrointestinal Function Recovery in Patients with Uterine Fibroids after Operation

YING Jiemin 1，FAN Juan1，YANG Biao 2，HUANG Jun 3，WU Xiaolong1

（1 Ma′anshan Central Hospital，Ma′anshan 243000，China; 2 Ma′anshan Shiqiye Hospital，Ma′anshan 243000，China; 3 Ma′anshan Women and Children Health Care Hospital，Ma′anshan 243000，China）

Abstract Objective：To explore the effects of Kangfu Xiaoyan Suppository on serum CRP，WBC levels and gastrointestinal function recovery in patients with uterine fibroids after surgery.Methods：A total of 80 patients with surgical treatment of uterine fibroids admitted to Ma′anshan Central Hospital from January 2017 to November 2017 were selected as the research objects，and according to random number table method，they were divided into a control group（n=40）and an observation group（n=40）.The control group given routine preventive postoperative Xiaoyan，and the observation group was given anal Kangfu Xiaoyan Suppository for the treatment.The patients′ treatment effect，anesthesia time，operating time，C-reactive protein（CRP）and white blood cells（WBC）and gastrointestinal functional recovery [postoperative exhaust time，postoperative defecation time] for the first time for the first time were compared.Results：After 7 days of treatment，the levels of CRP and WBC in 2 groups were lower than before treatment，and the levels of CRP and WBC in observation group were lower than control group（P<0.05）.There was no significant difference in operation time and anesthesia time between the 2 groups（P<0.05）.The contrast difference was statistically significant in the first postoperative exhaust time and the first postoperative defecation time in the observation group（t=3.232，2.729，P=0.002，0.008<0.05）.The total effective rate of the observation group was 95.00%，and that of the control group was 77.50%（P<0.05）.Conclusion：Kangfu Xiaoyan Suppositor can reduce postoperative inflammatory reaction and promote postoperative gastrointestinal function recovery in patients with uterine fibroids，which is worthy of promotion.

Keywords Kangfu Xiaoyan Suppository; Uterine fibroid surgery; C-reactive protein; White blood cells; Gastrointestinal function recovery; Inflammatory response; Abdominal distension.Curative effects

中图分类号：R289.5;R711.5文献标识码：Adoi：10.3969/j.issn.1673-7202.2021.09.020

子宫肌瘤属于妇科常见良性肿瘤之一，多见于30～55岁女性人群，很少发生在20岁女性人群[1]。大部分子宫肌瘤患者无特异临床症状，一般在健康体检时被检查出来，少数患者因为经期延长、经量增多、腰背酸痛、下腹坠胀、白带增多、下腹部包块等临床症状就诊。子宫肌瘤发病生理病理比较复杂，与孕激素及雌激素水平紧密相关，增加不孕风险[2-3]。对于本病，临床首选子宫肌瘤剔除术。随着腹腔镜技术发展，腹腔镜下子宫肌瘤剔除术在子宫肌瘤治疗中得到广泛应用，该手术机体创伤小，术后康复快[4]。尽管腹腔镜手术具有微创优点，但是术后患者也具有一定的并发症如感染、胃肠蠕动功能障碍等;手术对机体造成创伤，术后产生炎症反应，增加术后感染风险，也会引起机体内环境改变，不利于生命体征的稳定，不利于术后康复。……