刘志乐　　吴世皓　　华庆生　　黄韬　　陈远祥

[摘要] 目的 探討对于良性前列腺增生患者采用经尿道前列腺钬激光剜除手术治疗的临床效果，以及对患者IPSS和QOL所造成的影响。 方法 选择我院于2018年1月至2019年12月期间收治的良性前列腺增生患者80例作回顾性分析，按照治疗方式的不同进行分组，采用前列腺等离子切除术治疗的37例患者作为对照组，采用经尿道前列腺钬激光剜除术治疗的43例患者作为观察组。观察比较两组患者具体手术情况、治疗前后的IPSS与QOL指标变化以及术后并发症发生情况。 结果 ①观察组手术各项手术情况与对照组相比，差异有统计学意义（P均<0.05）。②两组患者治疗后IPSS和QOL评分显著优于治疗前（P均<0.05）;治疗后观察组IPSS和QOL评分优于对照组（P均<0.05）。③观察组患者并发症发生率低于对照组（P<0.05）。 结论 经尿道前列腺钬激光剜除术治疗良性前列腺增生，可有效减短患者住院治疗时间，患者恢复更快。且能显著提升患者IPSS和QOL评分，有效降低术后并发症的发生。

[关键词] 经尿道前列腺钬激光剜除术;前列腺等离子切除术;良性前列腺增生;临床疗效

[中图分类号] R697.32          [文献标识码] B          [文章编号] 1673-9701（2021）13-0065-04

Analysis on the clinical efficacy of transurethral holmium laser enucleation of prostate（HoLEP） in the treatment of benign prostatic hyperplasia and its impact on IPSS and QOL

LIU Zhile   WU Shihao   HUA Qingsheng   HUANG Tao   CHEN Yuanxiang

Department of Urology， Shunde Hospital of Southern Medical University， Foshan   528308， China

[Abstract] Objective To investigate the clinical efficacy of transurethral HoLEP for patients with benign prostatic hyperplasia and its impact on IPSS and QoL. Methods A total of 80 patients with benign prostatic hyperplasia admitted to our hospital from January 2018 to December 2019 were retrospectively analyzed and divided into the observation group （n=43） and the control group （n=37） according to different treatment methods. Patients in the control group were treated with prostatectomy， while those in the observation group were treated with transurethral HoLEP. The specific operation conditions， changes of IPSS and QoL indexes before and after treatment， and incidence of postoperative complications were observed and compared between the two groups of patients. Results ①There were statistically significant differences in operation conditions between the observation group and the control group（all P<0.05）. ②The IPSS and QoL scores of the two groups of patients after treatment were significantly superior to those before treatment （all P<0.05）. The IPSS and QoL scores of the observation group were superior to those of the control group after treatment （all P<0.05）. ③The incidence of complications in patients of the observation group was lower than that of the control group （P<0.05）. Conclusion Transurethral HoLEP on benign prostatic hyperplasia can effectively shorten the hospitalization time of patients and make them recover faster. Meanwhile， it can significantly improve IPSS and QOL scores of patients， and effectively reduce the incidence of postoperative complications.

[Key words] Transurethral holmium laser enucleation of prostate; Prostate plasma resection; Benign prostatic hyperplasia; Clinical efficacy

良性前列腺增生（Benign prostatic hyperplasia，BPH）是男性常见的外科疾病，临床上发生的患者多为中老年，临床研究发现，该疾病的发生率呈逐年上升的趋势，应当引起重点关注。在治疗方面，一般采用手术切除的方式，经尿道前列腺电切术（Transurethral prostatectomy，TURP）是目前治疗BPH最常用的术式之一，该术式虽然较成熟，但是对患者的选择有一定的限制，且术后容易出现各类并发症[1]。有鉴于此，近年来出现较多的新技术用于治疗BPH，其中经尿道前列腺等离子切除术（Plasmakinetic resection prostate，PKRP）与经尿道前列腺钬激光剜除术（ Holmium laser enucleation prostate，HoLEP）已开始广泛应用，并有望取代传统的TURP成为手术治疗BPH的新金标准[2]。本次研究将对比经尿道前列腺等离子切除术与经尿道前列腺钬激光剜除术对良性前列腺增生的治疗效果，现报道如下。……