周小芳　　顾敏洁　　方群

[摘要] 目的 探討宣痹汤泥灸治疗风寒湿痹型膝关节骨性关节炎的效果。 方法 选取2018年1月至2019年12月我院收治的风寒湿痹型膝关节骨性关节炎患者96例为研究对象，按照随机数字法分为两组，每组各48例。对照组采用常规治疗，观察组在对照组治疗基础上给予宣痹汤泥灸，观察两组患者治疗前后VAS评分和膝关节功能WOMAC评分，对比两组患者临床疗效和不良反应发生情况。 结果 治疗前两组患者的VAS评分比较，差异无统计学意义（P>0.05），治疗后2、4、8周，观察组VAS评分明显低于对照组，差异有统计学意义（P<0.05）。治疗前，两组患者膝关节功能WOMAC评分比较，差异无统计学意义（P>0.05），治疗后2、4、8周，观察组患者膝关节功能WOMAC评分低于对照组，差异有统计学意义（P<0.05）。治疗后8周，观察组治疗总有效率为89.58%，明显高于对照组的68.75%，差异有统计学意义（P<0.05）。两组患者不良反应总发生率比较（8.33% vs. 6.25%），差异无统计学意义（P>0.05）。 结论 宣痹汤泥灸辅助治疗膝关节骨性关节炎可以减轻患者疼痛程度，提高治疗效果，值得临床推广应用。

[关键词] 宣痹汤泥灸;风寒湿痹型;膝关节骨性关节炎;膝关节功能

[中图分类号] R684.3          [文献标识码] B          [文章编号] 1673-9701（2021）12-0138-04

Clinical research on mud moxibustion with Xuanbi Decoction in treatment of knee osteoarthritis of wind-cold-dampness bi

ZHOU Xiaofang   GU Minjie   FANG Qun

Department of Nursing，the Third Affiliated Hospital of Zhejiang Chinese Medical University，Hangzhou   310005，China

[Abstract] Objective To investigate the efficacy of mud moxibustion with Xuanbi Decoction in treating knee osteoarthritis of wind-cold-dampness bi. Methods A total of 96 cases of knee osteoarthritis of wind-cold-dampness bi admitted to our hospital from January 2018 to December 2019 were selected as the research objects， and they were divided into the control group（n=48） and the observation group （n=48） according to the random number table method. The control group was given conventional treatment，while the observation group was treated with mud moxibustion with Xuanbi Decoction on the basis of the treatment of the control group. The VAS score and WOMAC score of knee joint function were observed before and after treatment， and the clinical efficacy and adverse reactions（ADRs） of the two groups of patients were compared. Results There was no difference in VAS scores between the two groups before treatment（P>0.05）， and the VAS scores in the observation group were significantly lower than those in the control group after 2， 4， 8 weeks of treatment（P<0.05）. Before treatment， there was no significant difference in WOMAC score of knee joint function between the two groups（P>0.05）. However， after 2， 4， 8 weeks of treatment， the WOMAC score of knee joint function in the observation group was lower than that in the control group（P<0.05）. After 8 weeks of treatment， the total efficacy rate in the observation group was 89.58%， which was higher than that of 68.75% in the control group， with significant difference（P<0.05）. There was no significant difference in the total incidence of ADRs between the observation group and the control group（8.33% vs. 6.25%）（P>0.05）. Conclusion Mud moxibustion with Xuanbi Decoction as an auxiliary treatment for knee osteoarthritis can reduce the pain of patients and improve the therapeutic efficacy，which is worthy of clinical promotion and application.

[Key words] Mud moxibustion with Xuanbi Decoction; Wind-cold-dampness bi; Knee osteoarthritis; Knee joint function

膝关节骨性关节炎属于关节软骨的退行性变与继发性骨质增生，膝关节骨性关节炎中医称为“痹证”“骨痹”，中医认为病因病机为筋骨失荣、肝肾两虚以及瘀血阻滞，加之外伤﹑劳损影响，风寒湿邪侵体致病[1-2]。因此，临床上常表现为患肢麻痹﹑筋骨失荣﹑四肢拘挛，行走时关节有明显的疼痛感[3]。西医治疗主要是以非甾体类抗炎药联合使用改善病情、抗风湿类药物作为首选方案[4]。有关中药治疗膝骨性关节炎的研究逐渐展开，并取得较好的治疗效果[5]。本研究以2018年1月至2019年12月我院风寒湿痹型膝关节骨性关节炎患者96例作为研究对象，并观察西药联合宣痹汤泥灸治疗风寒湿痹型膝关节骨性关节炎的临床疗效，现报道如下。