叶文　　方晓红　　王连云　　熊文栋　　童夏　　王繁

[摘要] 目的 研究正念行走对高危孕妇预防子痫前期的可行性，同时评价正念行走与阿司匹林对子痫前期预防的有效性。 方法 选取2018年1月至2019年12月在温州医科大学附属第二医院产科治疗的妊娠期高血压高危孕妇，随机分为三组，均进行正常产检流程，试验组（n=28）进行正念行走锻炼，给药组（n=28）服用低剂量阿司匹林，对照组（n=31）无干预措施。分析三组高危孕妇的母胎结局。 结果 试验组和给药组孕妇妊娠期高血压发生率（10.71%、10.71%）略高于对照组（6.50%），但子痫前期发生率（3.60%、0.00%）显著低于对照组（22.60%），三组比较，差异有统计学意义（P<0.05）。对照组IUGR发生率（22.60%）高于试验组（0.00%）和给药组（10.71%），三组比较，差异有统计学意义（P<0.05）。试验组新生儿出生体重为（3503.57±402.52）g大于给药组的（3079.29±452.64）g和对照组的（3024.50±662.99）g，三组比较，差异有统计学意义（P<0.05）。 结论 高危孕妇孕期进行系统的正念行走干预或小剂量阿司匹林给药，均对子痫前期的发生具有一定预防作用，正念行走训练无经济压力、安全有效，可以作为预防子痫前期的有效措施之一。

[關键词] 妊娠期高血压;子痫前期;正念行走;高危孕妇

[中图分类号] R714.24          [文献标识码] B          [文章编号] 1673-9701（2021）12-0067-05

Study on the prevention of preeclampsia by mindful walking for high-risk pregnant women

YE Wen   FANG Xiaohong   WANG Lianyun   XIONG Wendong   TONG Xia   WANG Fan

Department of Obstetrics， the Second Affiliated Hospital of Wenzhou Medical University， Wenzhou   325000， China

[Abstract] Objective To study the feasibility of mindful walking in the prevention of preeclampsia for high-risk pregnant women， and to evaluate the effectiveness of mindful walking and aspirin in the prevention of preeclampsia. Methods The eligible pregnant women with high risk of hypertension during pregnancy were enrolled in the department of obstetrics in the Second Affiliated Hospital of Wenzhou Medical University from January 2018 to December 2019 were selected and randomly divided into three groups. All three groups were given a normal antenatal inspection process， the test group（n=28） was given mindful walking exercise， the medication group （n=28） was given low-dose aspirin， the control group （n=31） was given no intervention measures. The maternal and fetal outcomes of the three groups of high-risk pregnant women were analyzed. Results The prevalence of hypertension during pregnancy in the pregnant women in the test group and medication group （10.71%， 10.71%） was slightly higher than that in the control group （6.5%）. However， the incidence rate of preeclampsia （3.6%， 0.00%） was significantly lower than that in the control group （22.6%）， the differences between the three groups were statistically significant（P<0.05）. The incidence rate of fetal intrauterine growth restriction in the pregnant women in the control group （22.60%） was higher than that in the test group（0.00%） and medication group （10.71%）， the differences between the three groups were statistically significant （P<0.05）. The birth weight of newborns in the test group（3503.57±402.52） g was greater than that in the medication group（3079.29±452.64） g and the control group （3024.50±662.99） g， the differences between the three groups were statistically significant （P<0.05）. Conclusion Systematic mindful walking intervention or low-dose aspirin administration during pregnancy for high-risk pregnant women have a certain preventive effect on the occurrence of preeclampsia. Mindful walking training has no economic pressure， it is safe and effective， can be used as one of the effective measures to prevent preeclampsia.

[Key words] Pregnancy-induced hypertension; Preeclampsia; Mindful walking; High-risk pregnant women

妊娠期高血压是一种严重危害母婴安全的孕产期常见并发症，是导致孕产妇和围生儿疾病及死亡的主要原因之一。妊娠期高血压目前除终止妊娠外，尚无有效的治疗方法，因此，如何预防是目前研究的热点。近年来，补充与替代疗法预防子痫前期成为一种流行趋势，其中，中低强度运动对子痫前期有一定的保护作用[1-2]。正念觉知干预[3]作为一种安全、无介入的非药物治疗方式，也是一种微量运动方式，在减轻压力、改善抑郁[4]、降低血压[5]等方面具有显著的临床效果。作为正念觉知干预一个方面的正念行走干预，以其结合轻微运动和冥想干预为一体的优点，表现出增进精神健康的效应[6-7]。目前，临床有关正念行走与高危妊娠的研究较少，尚未见到正念行走与子痫前期预防的临床研究。……