新冠肺炎患者不同时期的CT表现及临床相关性分析
2021-06-02徐岱钦
徐岱钦

摘要:目的:分析不同时期新型冠状病毒肺炎(COVID-19)的CT表现及与临床的相关性。方法:对60例不同时期(急性期、恢复期)的COVID-19患者CT图像及临床指标进行对比分析。结果:相比于急性期,普通型患者在恢复期出现累及叶减少、病灶和磨玻璃影完全吸收的病例占比较重型、危重型多,而在恢复期较容易出现纤维化增多的情况或转化为磨玻璃影。T淋巴细胞亚群中的CD4+水平变化与患者病情进展有明显相关性。结论:COVID-19患者恢复期的NRCT征象较急性期明显缓解,且体内T淋巴细胞的水平变化与病情进展具有一定的相关性。
关键词:新型冠状病毒肺炎;CT;淋巴细胞
中图分类号:R563.1文献标识码:BDOI:10?郾3969/j.issn.1001-0270.2021.02.14
Novel Coronavirus Pneumonia Patients CT Manifestations and Clinical Correlation Analysis at Different Times
XU Dai-qin
(Department of Imaging, Headquarters of Suzhou Municipal Hospital, Jiangsu 215000, China)
Abstract: Objective: to analyze the CT manifestations and clinical correlation of New Coronavirus pneumonia (COVID-19) at different stages. Methods: the CT images and clinical indexes of 50 patients with cowid-19 in different periods (acute and convalescent) were compared and analyzed. Results: compared with the acute stage, the common type patients in the recovery stage had less involved lobes and complete absorption of lesions and ground glass shadow, which accounted for more severe and critical cases, while in the recovery stage, they were more likely to have increased fibrosis or turned into ground glass shadow. The level of CD4+ in T lymphocyte subsets was significantly correlated with the progression of the disease. Conclusion: the NRCT signs of convalescent patients with cowid-19 are better than those of acute patients, and there is a certain correlation between the level of T lymphocytes and the progress of the disease.
key words: New Coronavirus pneumonia; CT; lymphocytes
2019年末,一場由新型冠状病毒肺炎(COVID-19)引起的疫情从武汉蔓延开来。这是一种新型病毒引发的传染性极强的流行病,虽然我国在几个月时间内就对疫情进行了有效控制,但是在国外仍有较广泛的传播趋势[1]。这种病毒被世卫组织命名为2019-nCoV,可感染人体呼吸道上皮细胞,引起较为严重的肺部炎症。由于主要累及部位在肺部,因此CT诊断在此疾病的诊断治疗中起到了关键性的作用,对于病情的早期诊断和预后的分析有重要意义。现有研究发现,不同时期的患者CT表现有差异,且与临床指标存在一定的关联[2]。本次研究为了探讨这个问题,在本地区确诊的COVID-19患者中选取了60例作为研究对象。对其临床资料进行分析,具体内容如下。
1 资料与方法
1.1 一般资料
经上级批准收集本地区2020年2月-9月确诊的60例COVID-19患者病例资料,男性35例,女性25例,年龄范围18-76岁,平均(56.13±12.05)岁。……
