张玉茹

【摘要】 目的：探究臍动脉及大脑中动脉血流指标在胎儿宫内窘迫中的检测价值。方法：选取2019年1月-2020年8月于本院就诊的80例胎儿宫内窘迫孕妇为观察组，另选取同时期的80例正常孕妇为对照组。比较两组的脐动脉及大脑中动脉血流指标（S/D、PI及RI），同时比较观察组中不同胎儿生物物理评分者的脐动脉及大脑中动脉血流指标，并采用Spearman秩相关分析脐动脉、大脑中动脉血流指标与胎儿生物物理评分的关系。结果：观察组的脐动脉血流指标均高于对照组，大脑中动脉血流指标均低于对照组，且观察组中胎儿生物物理评分较低者的脐动脉血流指标均高于评分较高者，胎儿生物物理评分较低者的大脑中动脉血流指标均低于评分较高者，差异均有统计学意义（P<0.05）。Spearman秩相关分析显示，脐动脉血流指标与胎儿生物物理评分呈负相关（P<0.05），大脑中动脉血流指标与胎儿生物物理评分呈正相关（P<0.05）。结论：脐动脉及大脑中动脉血流指标在宫内窘迫胎儿中显著异常，且与严重程度密切相关，因此在胎儿宫内窘迫中的检测价值较高。

【关键词】 脐动脉 大脑中动脉 血流指标 胎儿宫内窘迫

Investigation on the Detection Value of Umbilical Artery and Middle Cerebral Artery Blood Flow Indexes of Fetus with Intrauterine Distress/ZHANG Yuru. //Medical Innovation of China， 2021， 18（05）： -117

[Abstract] Objective： To investigate the detection value of umbilical artery and middle cerebral artery blood flow indexes of fetus with intrauterine distress. Method： A total of 80 pregnant women with intrauterine distress admitted to our hospital from January 2019 to August 2020 were selected as the observation group， 80 normal pregnant women during the same period were selected as the control group. Then the umbilical artery and middle cerebral artery blood flow indexes （S/D， PI and RI） of two groups were compared， the umbilical artery and middle cerebral artery blood flow indexes of observation group with different fetal biophysical profile scores were compared， then the relationship between umbilical artery， middle cerebral artery blood flow indexes and fetal biophysical profile scores were analyzed with Spearman rank correlation analysis. Result： Umbilical artery blood flow index in observation group were higher than those of the control group， middle cerebral artery blood flow index were lower than those of the control group， fetal biophysical score lower in the observation group of umbilical artery blood flow index were higher than those of score high， fetal biophysical score lower middle cerebral artery blood flow index were lower than those of score high， the differences were statistically significant （P<0.05）. The Spearman rank correlation analysis showed the umbilical artery blood flow indexes were negatively correlated with fetal biophysical profile score （P<0.05）， the middle cerebral artery blood flow indexes were positively correlated with fetal biophysical profile score （P<0.05）. Conclusion： The umbilical artery and middle cerebral artery blood flow indexes of fetus with intrauterine distress are significantly abnormal， they have close relationship to the severity degree， so the detection value in the fetus with intrauterine distress are higher.

[Key words] Umbilical artery Middle cerebral artery Blood flow indexes Fetus with intrauterine distress

First-authors address： Peoples Hospital of Shiyan Economic Development Zone， Shiyan 442000， China

doi：10.3969/j.issn.1674-4985.2021.05.029

胎儿宫内窘迫可由多种因素导致，表现为宫内缺氧及酸中毒的情况，对其健康及生命安全造成极为不良的影响，因此是临床研究的重点。而对胎儿宫内窘迫的早期有效诊治是预后改善的重要前提。临床中与胎儿宫内窘迫相关的诊断检查研究中，胎儿血供相关方面的研究是重点[1-2]，而脐动脉及大脑中动脉血流作为与胎儿血供的重要检测与反应方面，其在胎儿宫内窘迫中变化研究可见的同时，研究结果的差异极为显著，有研究认为其对宫内窘迫的检查价值较高，但也有研究认为其与正常胎儿差异并不显著[3-5]。因此，本研究就脐动脉及大脑中动脉血流指标在胎儿宫内窘迫中的检测价值进行探究，现报道如下。……