任广军

【摘要】 目的：探讨血管栓塞术治疗脑动脉瘤患者的临床效果及对预后的影响。方法：选取2017年11月-2018年11月本院收治的脑动脉瘤患者90例。按随机数字表法分为研究组和对照组，各45例。对照组给予开颅夹闭术治疗，研究组给予血管栓塞术治疗。比较两组治疗效果、并发症发生情况、免疫功能指标及术后1年预后情况。结果：术后7 d，研究组CD3+、CD4+及CD4+/CD8+均高于对照组，且CD8+低于对照组（P<0.05）;研究组治疗总有效率高于对照组（P<0.05）;研究组并发症发生率低于对照组（P<0.05）;研究组术后1年预后情况优于对照组（P<0.05）。结论：血管栓塞术治疗脑动脉瘤患者可提高治疗总有效率，减少并发症的发生，促使患者免疫功能改善，预后良好，可推广使用。

【关键词】 脑动脉瘤 血管栓塞术 预后

Effect of Embolization in the Treatment of Cerebral Aneurysm and Its Effect on Prognosis/REN Guangjun. //Medical Innovation of China， 2021， 18（05）： 00-008

[Abstract] Objective： To investigate the clinical effect of embolization in the treatment of cerebral aneurysm and its effect on prognosis. Method： A total of 90 patients with cerebral aneurysm admitted to our hospital from November 2017 to November 2018 were selected. According to random number table method， they were divided into study group and control group， with 45 cases in each group. The control group was treated with craniotomy and clipping， while the study group was treated with embolization. The therapeutic efficacy， complications， immune function indexes and postoperative 1 year prognosis were compared between the two groups. Result： 7 d after surgery， CD3+， CD4+ and CD4+/CD8+ in the study group were higher than those in the control group， and CD8+ was lower than that in the control group （P<0.05）. The total effective rate of the study group was higher than that of the control group （P<0.05）. The complication rate of the study group was lower than that of the control group （P<0.05）. The postoperative 1 year prognosis of the study group was better than that of the control group （P<0.05）. Conclusion： Embolization in the treatment of cerebral aneurysm patients can improve the total effective rate， reduce the incidence of complications， improve the immune function of patients， and have a good prognosis， so it can be popularized.

[Key words] Cerebral aneurysm Embolization Prognosis

First-authors address： Shuangyashan Agricultural Reclamation Hongxinglong Administration Central Hospital， Shuangyashan 155811， China

doi：10.3969/j.issn.1674-4985.2021.05.002

腦动脉瘤属于临床上比较多见的脑血管疾病类型，如果患者出现一定程度的破裂、出血等症状，会使其意识以及肢体存在明显障碍[1]。若患者未及时接受科学合理的治疗，则极易导致动脉瘤再次发生破裂，使颅内出现大量血液，进而对患者生命健康造成严重威胁[2]。当前临床上多通过开颅手术等方式对患者实施治疗，但是对于部分动脉瘤所处位置较深的患者来说其治疗效果并不理想，且极易对患者身体造成一定创伤，并引发多种并发症[3]。血管内栓塞术的优势在于创伤性低、恢复迅速、促进患者神经功能改善等，因此在临床治疗中的应用愈发普遍[4]。本研究探讨血管栓塞术治疗脑动脉瘤患者的临床效果及对预后的影响，现报道如下。

1 资料与方法

1.1 一般资料 选取2017年11月-2018年11月本院收治的脑动脉瘤患者90例。纳入标准：病情完全符合脑动脉瘤的相关判断标准;精神状况不存在明显异常且未患有严重的脏器性疾病。排除标准：伴有一定程度的心肝肾功能异常且对术中麻醉药物难以耐受;存在开颅手术史且同时伴有严重的急慢性感染等疾病。……