刘兴龙 罗勤 黄文军 周国忠 姚常

【摘要】 目的：探究及分析NLR、PLR及心臟超声相关参数与急性ST段抬高型心肌梗死患者TIMI血流分级的关系。方法：选取2019年6月-2021年6月的120例急性ST段抬高型心肌梗死患者作为观察组，同时期的120名健康者作为对照组。比较两组NLR、PLR及心脏超声相关参数（LVEF、CO、WMSI、LAV、LVPW），同时比较观察组不同TIMI血流分级患者NLR、PLR及心脏超声相关参数，采用Spearman秩相关分析NLR、PLR及心脏超声相关参数与急性ST段抬高型心肌梗死TIMI血流分级的关系。结果：观察组NLR、PLR、WMSI及LVPW均显著高于对照组，LVEF、CO及LAV均显著低于对照组，观察组不同TIMI血流分级患者NLR、PLR及心脏超声相关参数比较，差异均有统计学意义（P<0.05）。Spearman秩相关显示NLR、PLR、WMSI及LVPW与急性ST段抬高型心肌梗死TIMI血流分级均呈负相关（P<0.05），LVEF、CO及LAV与急性ST段抬高型心肌梗死TIMI血流分级均呈正相关（P<0.05）。结论：NLR、PLR及心脏超声相关参数在急性ST段抬高型心肌梗死患者中差异显著，且与本类患者的TIMI血流分级关系密切，在本类患者中的检测价值较高。

【关键词】 NLR PLR 心脏超声相关参数 急性ST段抬高型心肌梗死 TIMI血流分级

Investigation on Correlation between NLR， PLR， Cardiac Ultrasound Related Parameters and TIMI Blood Flow Classification of Patients with Acute ST-segment Elevation Myocardial Infarction/LIU Xinglong， LUO Qin， HUANG Wenjun， ZHOU Guozhong， YAO Chang. //Medical Innovation of China， 2021， 18（33）： -126

[Abstract] Objective： To investigate and analyze the correlation between NLR， PLR， cardiac ultrasound related parameters and TIMI blood flow classification of patients with acute ST-segment elevation myocardial infarction. Method： A total of 120 patients with acute ST-segment elevation myocardial infarction from June 2019 to June 2021 were chosen as the observation group， 120 healthy persons at the same time were chosen as the control group. Then the NLR， PLR and cardiac ultrasound related parameters （LVEF， CO， WMSI， LAV， LVPW） of two groups were compared， the NLR， PLR and cardiac ultrasound related parameters of the observation group with different TIMI blood flow classification were compared too， and the NLR， PLR， cardiac ultrasound related parameters and TIMI blood flow classification of acute ST-segment elevation myocardial infarction were analyzed by Spearman rank correlation analysis. Result： The NLR， PLR， WMSI and LVPW of the observation group were significantly higher than those of the control group， the LVEF， CO and LAV were significantly lower than those of the control group， NLR， PLR and cardiac ultrasound related parameters of observation group with different TIMI blood flow classification were compared， there were statistically significant differences （P<0.05）. Spearman rank correlation showed that NLR， PLR， WMSI and LVPW were negatively correlated with TIMI blood flow classification of acute ST-segment elevation myocardial infarction （P<0.05）， the LVEF， CO and LAV were positively correlated with TIMI blood flow classification of acute ST-segment elevation myocardial infarction （P<0.05）. Conclusion： The differences of NLR， PLR， cardiac ultrasound related parameters of patients with acute ST-segment elevation myocardial infarction are significant， and they have close relationship with TIMI blood flow classification， so their detection value in these patients are high.

[Key words] NLR PLR Cardiac ultrasound related parameters Acute ST-segment elevation myocardial infarction TIMI blood flow classification

First-author’s address： People’s Hospital of Pingxiang， Pingxiang 337000， China

doi：10.3969/j.issn.1674-4985.2021.33.030

急性ST段抬高型心肌梗死的临床危害显著，病死率较高，是临床治疗时效性要求极高的一类疾病，因此临床中对急性ST段抬高型心肌梗死的诊治研究均较多[1-2]。近年来关于NLR、PLR在急性心肌梗死患者中的表达变化研究多见，但是针对急性ST段抬高型心肌梗死的研究差异也普遍存在，且与TIMI血流分级的关系研究不足，导致其在本病预后评估与判断中的参考价值不足[3-5]，因此本方面的细致探究意义较高。……