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功能性消化不良患者胃电图特点

2021-01-05陈洪锁年媛媛孟宪梅王学勤

中国现代医生 2021年30期

陈洪锁 年媛媛 孟宪梅 王学勤

[摘要] 目的 探討功能性消化不良(Functional dyspepsia,FD)患者胃电图(EGG) 特点。 方法 对2012年1月至2017年12月就诊于西安交通大学第一附属医院159例入组患有功能性消化不良症状的患者,均符合RomeIV FD诊断标准,其中包括上腹痛综合征(Epigastric pain syndrome,EPS)[男39例,女37例,平均年龄(42.88±13.12)岁]、餐后不适综合征(post prandial distress syndrome,PDS)[男28例,女55 例,平均年龄(40.73±13.06 岁)]和53例健康人[其中男22 例,女31例,年龄(41.15±11.51)岁]。 结果 EGG监测显示,静息、餐后胃电节律百分率EPS组为(34.88±9.16)%和(41.69±9.87)%、PDS 组为(43.96±11.88)%和(49.67±10.85)%,低于正常对照组的(87.4±14.85)%和(86.83±12.23)%,三组比较,差异有统计学意义(P<0.05);胃电节律过缓的百分率EPS组(56.26±10.23)%和(43.00±10.13)%、PDS组(45.41±14.90)%和(37.54±5.02)%明显高于正常对照组的(10.09±2.11)%和(9.22±2.55)%(P<0.05),胃电节律过速的百分率EPS(56.26±10.23)%和(13.16±3.95)%、PDS组为(6.64±1.08)%和(37.54±7.02)%,明显高于正常对照组的(1.78±0.23)%和(2.83±0.21)%,差异均有统计学意义(P<0.05)。 结论 功能性消化不良患者餐前餐后胃电节律异常,以胃动过缓为主,提示 FD患者存在胃运动功能障碍,胃电图对阐明 FD的发生机制有一定的临床意义。

[关键词] 功能性消化不良;上腹痛综合征;餐后不适综合征;胃电图;胃电节律

[中图分类号] R570.4          [文献标识码] B          [文章编号] 1673-9701(2021)30-0103-03

[Abstract] Objective To investigate the characteristics of electrogastrography (EGG) in patients with functional dyspepsia (FD). Methods A total of 159 patients with functional dyspepsia admitted to the First Affiliated Hospital of Xi′an Jiaotong University from January 2012 to December 2017 were enrolled. All patients met RomeIVFD diagnostic criteria, including epigastric pain syndrome (EPS) (39 males and 37 females, average age 42.88±13.12 years), postprandial distress syndrome (PDS) (28 males and 55 females,average age (40.73±13.06)years and 53 healthy subjects (22 males and 31 females,average agewas (41.15±11.51)years. Results EGG monitoring showed that the percentage of resting postprandial gastric electrical rhythm was (34.88±9.16)% and (41.69±9.87% in EPS group, (43.96±11.88)% and (49.67±10.85)% in the PDS group, which was lower than (87.4±14.85)% and (86.83±12.23)% in the normal control group (P<0.05); the percentage of bradygastria EGG domain frequency was (56.26±10.23)% and (43.00±10.13)% in the EPS group, (45.41±14.90)% and (37.54±5.02)% in the PDS group, which was significantly higher than (10.09±2.11)% and(9.22±2.55)% in the normal control group(P<0.05); the percentage of tachygastria EGG domain frequency was (56.26±10.23)% and (13.16±3.95)% in the EPS group,(6.64±1.08)% and (37.54±7.02)% in the PDS group, which was significantly higher than (1.78±0.23)% and (2.83±0.21)% in the normal control group, and the difference was significant(P<0.05). Conclusion Patients with functional dyspepsia have abnormal gastric electrical rhythm before and after meals, mainly bradygastria EGG domain frequency, suggesting that FD patients have gastric motor dysfunction. Electrogastrography has certain clinical significance in elucidating the mechanism of FD.

[Key words] Functional dyspepsia; Epigastric pain syndrome; Discomfort syndrome; Electrogastrography; Gastric electrical rhythm

功能性消化不良(Functional dyspepsia,FD)是一种常见的功能性胃肠病,是一种以上消化道症状为主的综合征;具体表现为上腹部疼痛或烧灼感、餐后饱胀、早饱、嗳气等,功能性消化不良有上腹痛综合征(Epigastricpain syndrome,EPS)、餐后不适综合征(Postprandialdistress syndrome,PDS)两种临床亚型。通过临床评估其他疾病无法完全解释其症状。FD是一种比较顽固的消化道疾病,由于其反复发作的特点,不仅损害患者的身心健康,而且占用大量医疗资源。目前,药物、心理干预对FD的治疗效果还有待进一步证实。……

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