魏星 常勇

【摘 要】 目的：观察中西医结合治疗对冠心病稳定型心绞痛患者的运动耐量和心肌缺血的影响。方法：将73例稳定型心绞痛患者随机分为2组，对照组37例，观察组36例。对照组予冠心病常规西药治疗，观察组在对照组基础上加用诺迪康胶囊，治疗周期均为8周。治疗前后两组均完善心电图及运动平板实验，观察并记录相关指标。结果：治疗8周后，在改善心肌缺血方面，两组治疗后心电图缺血导联ST压低水平均较治疗前减低，且观察组优于对照组，差异有统计学意义（P<0.05），在改善运动耐量方面，治疗后观察组运动时间明显长于对照组（P<0.05）。结论：中西医结合治疗在改善冠心病稳定型心绞痛患者的心肌缺血、提高运动耐量方面疗效较好。

【关键词】 稳定型心绞痛;诺迪康;运动耐量;心肌缺血

【中图分类号】R541.4   【文献标志码】 A    【文章编号】1007-8517（2020）9-0106-04

Clinical observation of 36 cases of coronary heart disease treated by integrated Chinese and western medicine

WEI Xing CHANG Yong*

Guangzhou Hospital of Traditional Chinese Medicine，Guangzhou 510000，China

Abstract：ObjectiveTo observe the effects of Nuo Di kang on myocardial ischemia and motion-endurance of the patients with stable angina.MethodsSeventy - three patients with stable angina  were randomly divided into two groups：The control group have 37 patients and the observation group have 36 patients. The control group to the coronary heart disease （CHD） conventional western medicine treatment; On the basis of control group and observation group with di kang capsule， treatment period for 8 week. both groups need to performed the Electrocardiogram and treadmill exercise test before and after treatment. Observe and record the related indexes. ResultsAfter 8 weeks of treatment， the level of ST depression of ECG in the two groups was lower than that before treatment， the observation group was better than the control group in clinical efficacy， the difference between the two groups has statistically significant （P<0.05），In terms of improving exercise tolerance， the exercise time in the observation group after treatment was significantly longer than that in the control group（P<0.05）. ConclusionNuo Di kang Capsule is safe and effective in improving myocardial ischemia and improving exercise tolerance in patients with stable angina.

Key words：stable angina;Nuo Di Kang; motion-endurance;Myocardial Ischemia

冠心病（coronary atherosclerotic heart disease，CHD）是指冠狀动脉（冠脉）发生粥样硬化引起管腔狭窄或闭塞，导致心肌缺血缺氧或者坏死而引起的心脏病，也称缺血性心脏病[1]。近年来其发病率不断增高，已成为中老年患者的主要致死因素，严重威胁人类的健康。因此探索冠心病的防治方法，已成为临床研究热点之一。纯中药制剂诺迪康，主要原料为红景天，主要成分为红景天苷、黄酮等，大量动物及人体试验研究证实诺迪康有扩张冠脉、调脂、改善心肌缺血缺氧、降低血液黏度、保护神经细胞等作用，现已广泛应用于心脑血管疾病的防治，且安全性佳[2]。本研究应用常规西药联合诺迪康胶囊治疗冠心病稳定型心绞痛，观察其对稳定型心绞痛患者运动耐量及心肌缺血的影响，现报道如下。

1 资料与方法

1.1 一般资料 观察病例为广州市中医医院2017年1月至2018年10月门诊及住院患者，诊断为：冠心病稳定型心绞痛，证属气虚血瘀者。……