刘璐　毛拥军　冯媛媛　胡松　薛晓霞　宫婷

[摘要] 目的 了解老年住院病人营养风险、血清尿酸水平、尿酸与营养状态的相关性以及血清尿酸对营养风险的识别。

方法 收集某三甲医院的129例老年住院病人一般资料（包括年龄、性别、教育程度、疾病史），行体格检测（测量身高、体质量、上臂围、小腿围），采用营养风险筛查2002评估表（NRS2002）进行营养风险筛查，实验室检测血红蛋白、清蛋白、总蛋白、前清蛋白、血清尿酸等指标，分析尿酸与营养状態的相关性及尿酸水平对营养风险的识别能力。

结果 老年住院病人营养风险发生率为62.8%，消瘦发生率为8.5%，高尿酸血症比例为34.9%。营养风险与年龄、教育程度、疾病（肿瘤）、体质量指数、上臂围、小腿围、前清蛋白、总蛋白、清蛋白、血红蛋白均显著相关（r=-0.484～0.282，P<0.01）。血清尿酸低水平和高水平识别营养风险差异有显著意义（95%CI=0.582～0.784，P<0.05）。

结论 老年住院病人营养风险发生率高，血清尿酸低水平及高水平均需警惕营养风险发生。

[关键词] 老年人;营养不良;营养评价;营养调查;尿酸

[中图分类号] R589.2

[文献标志码] A

[文章编号] 2096-5532（2020）03-0297-04

doi：10.11712/jms.2096-5532.2020.56.086

[开放科学（资源服务）标识码（OSID）]

[网络出版] http：//kns.cnki.net/kcms/detail/37.1517.R.20200519.1443.012.html;2020-05-19 17：23

RELATIONSHIP BETWEEN URIC ACID LEVEL AND NUTRITIONAL STATUS IN ELDERLY INPATIENTS

LIU Lu， MAO Yongjun， FENG Yuanyuan， HU Song， XUE Xiaoxia， GONG Ting

（Department of Geriatric Medicine， The Affiliated Hospital of Qingdao University， Qingdao 266003， China）

[ABSTRACT]ObjectiveTo observe the serum uric acid level and nutritional risk in elderly inpatients， and to explore the correlation between serum uric acid and nutritional status， as well as the ability of serum uric acid for identifying nutritional risk.

MethodsGeneral information （including age， sex， educational level， and medical history） was collected from 129 elderly inpatients in No. 971 Hospital of Peoples Liberation Army Navy. Physical examination （measurement of body height， body weight， upper arm circumference， and calf circumference） was performed. Nutritional Risk Screening 2002 （NRS2002） was used to screen for the nutritional risk. Laboratory markers were measured， including hemoglobin， albumin， total protein， prealbumin， serum uric acid. Analyses were performed on the correlation between uric acid and nutritional status， as well as the ability of uric acid level for identifying the nutritional risk.

ResultsThe incidence of nutritional risk， emaciation， and hyperuricemia was 62.8%， 8.5%， and 34.9%， respectively， in elderly inpatients. Nutritional risk was significantly correlated with age， educational level， disease （tumor）， body mass index， upper arm circumference， calf circumference， prealbumin， total protein， albumin， and hemoglobin （r=-0.484-0.282，P<0.01）. There was a significant difference in identifying nutritional risk between low and high levels of se-

rum uric acid （95%CI=0.582-0.784，P<0.05）.

ConclusionElderly inpatients are at high risk of malnutrition. When their serum uric acid level is either low or high， nutritional risk should be watched out for.

[KEY WORDS]aged; malnutrition; nutrition assessment; nutrition surveys; uric acid

老龄化社会是指一个国家或地区65岁及以上的人口占该国家或地区人口总数的7%或以上[1]。2000年我国65岁及以上人口比例达到7.0%，至2018年该比例已达到11.9%，表明我国老龄化问题正逐渐加剧[2]。中国疾病负担研究表明，2016年我国居民期望寿命为76.4岁，而健康期望寿命仅为67.9岁[3]。在老龄化问题极为严峻的今天，健康老龄化受到越来越多的关注。研究表明，营养不良与10年心血管风险、认知功能、病死率、全因死亡等相关[4-6]。……