莫灿均 张志成

[摘要]目的 探討胫前静脉途径多介入模式溶栓治疗急性下肢深静脉血栓的效果。方法 选取2014年1月～2017年12月我院收治的90例急性下肢深静脉血栓患者作为研究对象，采取随机数字表法将其分成常规组以及实验组，每组各45例。常规组患者予以腘静脉置管溶栓治疗，实验组患者予以经胫前静脉途径多介入模式溶栓治疗。比较两组患者的血栓清除效果、并发症发生情况、住院时间以及随访情况。结果 实验组患者的血栓清除效果优于常规组，差异有统计学意义（P<0.05）。实验组患者的并发症总发生率（4.44%）低于常规组（24.44%），差异有统计学意义（P<0.05）。实验组患者的住院时间短于常规组，差异有统计学意义（P<0.05）;实验组患者的不良事件总发生率（2.22%）低于常规组（20.00%），差异有统计学意义（P<0.05）。结论 急性下肢深静脉血栓患者采用胫前静脉途径多介入模式溶栓治疗可提升血栓清除效果，减少并发症的发生，缩短住院时间，降低不良事件发生率，值得临床广泛应用。

[关键词]急性下肢深静脉血栓;多介入模式;经胫前静脉

[中图分类号] R543.6          [文献标识码] A          [文章编号] 1674-4721（2020）5（b）-0049-03

Effect of multiple intervention modes via anterior tibial vein approach in the treatment of acute deep venous thrombosis of lower extremity

MO Can-jun   ZHANG Zhi-cheng▲

Department of Intervention， Dongguan People′s Hospital， Guangdong Province， Dongguan   523000， China

[Abstract] Objective To discuss the effect of multiple intervention modes via anterior tibial vein approach in the treatment of acute deep venous thrombosis of lower extremity. Methods A total of 90 patients with acute deep venous thrombosis of lower extremity from January 2014 to December 2017 treated in our hospital were chosen as research subjects. According to the random number table method， the patients were assigned to conventional group and test group， 45 cases in each group. The conventional group took the thrombolytic therapy via popliteal vein approach; the test group took the multiple intervention modes via anterior tibial vein approach. The thrombosis removal effect， incidence of complications， hospital stay and follow-up results were compared. Results The thrombosis removal effect in the test group was better than that in the conventional group， with statistically significant difference （P<0.05）. The total incidence rate of complications in the test group （4.44%） was lower than that in the conventional group （24.44%）， with statistically significant difference （P<0.05）. The hospital stay in the test group was shorter than that in the conventional group， with statistically significant difference （P<0.05）. The total incidence rate of adverse events in the test group （2.22%） was lower than that in the conventional group （20.00%）， with statistically significant difference （P<0.05）. Conclusion For patients with acute deep venous thrombosis of lower extremity， the use of multiple intervention modes via anterior tibial vein approach can improve the thrombosis removal effect， reduce the incidence of complications， shorten the hospital stay， and reduce the incidence rate of adverse events， which is worthy of clinical application.

[Key words] Acute deep venous thrombosis of lower extremity; Multiple intervention modes; Anterior tibial vein

下肢深静脉血栓在周围血管疾病中属于较为常见的一种疾病，由于人们生活方式的改变，导致疾病发病率不断升高[1]。临床认为导致下肢深静脉血栓形成的主要原因包括：静脉血流速度减缓、静脉血管壁受损以及血液处于高凝状态[2]。下肢深静脉血栓形成后，若不及时进行有效治疗，极易出现血栓蔓延情况以及肺动脉栓塞，对患者生命安全产生严重威胁。对于下肢深静脉血栓治疗临床研究较多，但通过胫前静脉途径治疗临床研究不足[3]。因此，本研究选取我院收治的90例急性下肢深静脉血栓患者作为研究对象，旨在探讨胫前静脉途径多介入模式溶栓治疗急性下肢深静脉血栓的效果，现报道如下。

1资料与方法

1.1一般资料

选取2014年1月～2017年12月我院收治的90例急性下肢深静脉血栓患者作为研究对象，采取随机数字表法将其分成常规组以及实验组，每组各45例。……