代跃荣

【摘  要】目的：研究急性痛风性关节炎患者采用四妙丸加味方案进行治疗的临床效果。方法：选择在我院接受药物治疗的88例急性痛风性关节炎患者，以随机分组的方式将其分成对照组（44例）和治疗组（44例）。对照组采用塞来昔布进行治疗;治疗组在塞来昔布基础上，采用四妙丸加味方案进行治疗。结果：治疗组患者药物治疗总有效率达到90.9%，高于对照组的70.5%;治疗前后疼痛程度评分、白细胞计数、血尿酸水平的改善幅度大于对照组;关节疼痛症状消失时间、住院治疗时间、关节功能恢复正常时间短于对照组;仅有2例药物不良反应，少于对照组的9例。有统计学意义（P<0.05）。结论：急性痛风性关节炎患者采用四妙丸加味方案进行治疗，可以大幅度降低白细胞和血尿酸水平，在短时间内减轻疼痛，缩短病情恢复时间和治疗时间，降低药物不良反应发生率，使治疗效果显著提升。

【关键词】急性;痛风性关节炎;四妙丸;疼痛;血尿酸;白细胞

【中图分类号】R259      【文献标识码】A      【文章编号】1004-7484（2019）07-0096-01

【Abstract】Objective： To study the clinical effect of Simiao pill in the treatment of acute gouty arthritis.Methods：88 patients with acute gouty arthritis were randomly divided into control group （44 cases） and treatment group （44 cases）. The control group was treated with celecoxib，while the treatment group was treated with Simiao pill based on celecoxib.Results：the total effective rate of drug treatment in the treatment group was 90.9%，which was higher than 70.5% in the control group; the improvement of pain score，leukocyte count and blood uric acid level before and after treatment was greater than that in the control group;the time of disappearance of joint pain symptoms， hospitalization and recovery of joint function was shorter than that in the control group;only 2 cases of adverse drug reactions were less than that in the control group.There was statistical significance（P<0.05）. Conclusion： the treatment of acute gouty arthritis patients with Modified Simiao pill can significantly reduce the level of leukocyte and blood uric acid，relieve pain in a short time， shorten the recovery time and treatment time，reduce the incidence of adverse drug reactions， and significantly improve the treatment effect.

【Key words】acute;gouty arthritis;Simiao pill;pain;blood uric acid;leukocyte

痛風具体指的是由于遗传性或获得性嘌呤代谢功能紊乱和尿酸排泄功能障碍而导致出现的一组综合征类疾病，无症状高尿酸血症、痛风石、慢性或急性痛风性关节炎等属于该病患者在发病后的主要症状表现。随着近些年来人们生活习惯的不断改变，其饮食结构也在发生着变化，痛风的临床患病率水平呈现明显增高的太晒。急性痛风性关节炎属于临床上常见的一种痛风类型，以下肢关节部位发病的可能性最高^[1]。……