缺铁性贫血和地中海贫血患者的血液检验与结果研究
2019-09-29田丽萍李硕辉
田丽萍 李硕辉


【摘要】 目的:探讨贫血患者的血液检验及其检验结果。方法:选取2016年5月-2018年5月本院收治的经临床确诊为贫血患者50例,依贫血类型分为缺铁性贫血组30例和地中海贫血组20例,同时将同期接待的健康体检者50例为对照组。所有对象均接受血液检验,比较各组血液检验指标(RBC、MCV、Hb、MCH、RBC/MCV、RDW),分析缺铁性贫血与地中海贫血符合率。结果:三组MCV、Hb、RBC/MCV、RDW比较差异均有统计学意义(P<0.05),三组RBC、MCH比较差异均无统计学意义(P>0.05);其中地中海贫血组RBC、MCV、Hb、MCH、RDW均低于对照组(P<0.05),RBC/MCV高于对照组(P<0.05);缺铁性贫血组MCV、Hb、MCH、RBC/MCV均低于对照组(P<0.05),RDW高于对照组(P<0.05);地中海贫血组RBC、RDW均低于缺铁性贫血组(P<0.05),Hb、RBC/MCH均高于缺铁性贫血组(P<0.05);地中海贫血组、缺铁性贫血组经血液检验符合率分别为80.00%、83.33%,比较差异无统计学意义(P>0.05)。结论:血液检验应用在贫血患者中有一定的诊断价值,可以作为辅助参考指标,可为臨床诊治贫血提供一定的参考,值得在基层医院推广。
【关键词】 贫血; 地中海贫血; 缺铁性贫血; 血液检验
Blood Tests and Results of Iron Deficiency Anemia and Thalassemia/TIAN Liping,LI Shuohui.//Medical Innovation of China,2019,16(06):0-042
【Abstract】 Objective:To investigate the blood test and test results of anemia patients.Method:A total of
50 patients with anemia diagnosed clinically in our hospital from May 2016 to May 2018 were selected and divided into iron deficiency anemia group(n=30)and thalassemia group(n=20)according to the type of anemia,at the same time,50 health examinees received in the same period were taken as control group.All subjects were tested by blood test.The blood test indexes(RBC,MCV,Hb,MCH,RBC/MCV,RDW)of each group were compared,and the coincidence rate between iron deficiency anemia and Mediterranean anemia was analyzed.Result:The MCV,Hb,RBC/MCV and RDW in three groups were compared,the differences were statistically significant(P<0.05),the RBC and MCH were compared,the differences were not statistically significant(P>0.05).The RBC,MCV,Hb,MCH and RDW in thalassemia group were lower than those of control group(P<0.05),and RBC/MCV was higher than that of control group(P<0.05).The MCV,Hb,MCH,RBC/MCV in iron deficiency anemia group were lower than those of control group(P<0.05),and RDW was higher than that of control group(P<0.05).The RBC and RDW in thalassemia group were lower than those of iron deficiency anemia group(P<0.05),while Hb and RBC/MCH in thalassemia group were higher than those of iron deficiency anemia group(P<0.05).The coincidence rates of blood tests in thalassemia group and iron deficiency anemia group were 80.00% and 83.33% respectively,the difference was not statistically significant(P>0.05).Conclusion:The application of blood test in patients with anemia has certain diagnostic value,can be used as an auxiliary reference index,can provide a certain reference for clinical diagnosis and treatment of anemia,and is worth of promoting in grass-roots hospitals.
【Key words】 Anemia; Thalassemia; Iron deficiency anemia; Blood test
First-authors address:Taishan Peoples Hospital,Taishan 529200,China
doi:10.3969/j.issn.1674-4985.2019.06.010
贫血属于临床比较常见的疾病,常见的类型主要是地中海贫血与缺铁性贫血,但二者发病机制不同,治疗方案也有所不同,为此需进行必要的鉴别诊断,才能促进治疗更有针对性[1]。从有关报道中看出,很多系统疾病均可能造成贫血发生,而不同原因所致贫血症状都有着相似的血液学特征与临床表现,这些都会导致临床诊断难度较大[2-6]。按照世界卫生组织研究报道可知,全球有>25%人群罹患贫血,而血红蛋白、红细胞酶、红细胞膜基因不足等所致贫血在人类遗传疾病中高居病因首位[7]。血液检验在临床检验中有着广泛的应用,也是血常规检验中最为基本的方式。血液包括液体与有形细胞两部分,血常规检验主要涉及的是血液细胞部分,血液细胞含有三种细胞,包括红细胞、白细胞、血小板,主要是通过观察这些细胞的数量变化与形态分布来进行疾病判断。为……
