乌司他丁联合生长抑素治疗糖尿病合并急性胰腺炎效果研究
2019-09-17夏国栋杨柏新陈竟男
夏国栋 杨柏新 陈竟男
[摘要] 目的 探讨乌司他丁联合生长抑素治疗糖尿病合并急性胰腺炎的效果。方法 选取该科2016年11月—2018年11月收治的糖尿病合并急性胰腺炎患者38例,随机分为两组,各19例,观察组采用乌司他丁联合生长抑素治疗,对照组采用生长抑素治疗。结果 观察组有效率为94.7%,显著高于对照组73.7%(P<0.05);观察组FPG、腹痛症状消失时间、平均住院时间显著优于对照组(P<0.05)。结论 乌司他丁联合生长抑素治疗糖尿病合并急性胰腺炎效果显著,可有效改善患者症状,控制血糖,提高治愈率。
[关键词] 乌司他丁;生长抑素;糖尿病;急性胰腺炎
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2019)06(b)-0099-02
[Abstract] Objective To investigate the effect of ulinastatin combined with somatostatin on diabetic patients with acute pancreatitis. Methods A total of 38 patients with diabetes mellitus complicated with acute pancreatitis admitted to our department from November 2016 to November 2018 were randomly divided into two groups: 19 patients each. The observation group was treated with ulinastatin and somatostatin. The control group was treated with somatostatin treatment. Results The effective rate of the observation group was 94.7%, which was significantly higher than that of the control group (73.7%)(P<0.05). The time of disappearance of FPG, abdominal pain and average hospitalization time in the observation group were significantly better than those in the control group(P<0.05). Conclusion Ulinastatin combined with somatostatin is effective in the treatment of diabetes with acute pancreatitis, which can effectively improve the symptoms, control blood glucose and improve the cure rate.
[Key words] Ulinastatin; Somatostatin; Diabetes; Acute pancreatitis
急性胰腺炎是臨床多见的急腹症,近年来,因各种不良因素的影响,急性胰腺炎发病率不断呈增高趋势,由于其发病迅猛,病情险恶,可导致严重的并发症甚至死亡。报道显示[1],我国急性胰腺炎每年的发病率为13~45/10万,而病死率则高达20%以上。糖尿病是常见的慢性代谢性疾病,其与疾病的发生、发展、治疗密切相关。有研究表明糖尿病是导致胰腺疾病的高危因素之一[2],严重影响患者血糖控制和病情发展。对该科2016年11月—2018年11月收治的38例糖尿病合并急性胰腺炎患者采用乌司他丁联合生长抑素治疗并观察,报道如下。
1 资料与方法
1.1 一般资料
选取该科收治的糖尿病合并急性胰腺炎患者38例为观察对象,随机分为两组各19例。观察组男11例,女8例,年龄26~61岁,平均(43.2±2.0)岁,糖尿病病程3~10年,平均(5.6±0.8)年,发病时间3~8 h,平均(5.1±1.1)h,病因:胆源性10例、酒精性6例、其它3例;对照组男12例,女 7例,年龄24~62岁,平均(44.1±1.9)岁,糖尿病病程3~9年,平均(5.9±1.0)年,发病时间3~8 h,平均(5.1±1.1)h,病因:胆源性8例、酒精性7例、其它4例。患者均知情同意并经伦理委员会批准。两组患者一般资料比较差异无统计学意义(P>0.05)。……p>
