卵圆孔未闭PFO合并反常栓塞行介入封堵治疗的效果及安全性分析
2019-08-09刘云兵
【摘要】目的:研究患有卵圆孔未闭(PFO)合并反常栓塞的患者通过实施介入封堵治疗的临床效果以及临床安全性。方法 : 在我院选取58名已经经过临床确诊患有卵圆孔未闭(PFO)合并反常栓塞的病患,其中患有偏头痛的患者有20名,患有短暂性脑部缺血发作的患者有25名以及不确定因素导致心肌梗死的13名。对此58名患者实施PFO介入封堵进行临床治疗,记录对比所有患者在治疗前和治疗之后的第3、30、90、180天的经胸超声心动图(cTTE) 右心声学造影以及经颅超声多普勒(cTCD) 声学造影结果。结果:本次治疗总计有53名患者封堵成功,封堵成功概率为91%,并且58名患者在治疗后其cTCD/cTTE 声学造影结果相对良好。结论:对于患有PFO合并反常栓塞的患者,采用介入封堵进行治疗具有良好的治疗价值以及较高的安全性,值得临床应用推广实施。
【关键词】卵圆孔未闭(PFO)合并反常栓塞;介入封堵
【中图分类号】R541 1
【文献标志码】A
【文章编号】
1005-0019(2019)16-039-01
Abstract
Objective: to study the clinical efficacy and safety of interventional occlusion in patients with patent foramen ovale (PFO) complicated with abnormal embolism. Methods: 58 patients with clinically diagnosed patent foramen ovalis (PFO) complicated with abnormal embolism were selected in our hospital, including 20 patients with migraine, 25 patients with transient ischemic attack and 13 patients with myocardial infarction caused by uncertain factors. A total of 58 patients were clinically treated with PFO occlusion, and contrast-enhanced transcranial echocardiography (cTTE) of the right voice and transcranial doppler echocardiography (cTCD) were recorded before and after treatment at 3, 30, 90 and 180 days. Results: a total of 53 patients were successfully occluded in this treatment, with a 91% probability of occlusion success, and the acoustic contrast Results of cTCD/cTTE were relatively good in 58 patients after treatment. Conclusion: for patients with PFO complicated with abnormal embolism, interventional occlusion has good therapeutic value and high safety, which is worthy of clinical application and implementation.
Key words:
patent foramen ovale (PFO) combined with anomalous embolism, interventional occlusion
前言
隨着我国的医疗技术不断提高,在长期的临床治疗之中发现气体栓塞、脑血栓以及人们在潜水的时候引发的神经减压病等极有可能是和反常栓塞有密切的联系。由于反常栓塞在临床上往往表现出其多样性,其中主要表现以偏头痛、不明因素脑卒中等症状为主,同时也有可能是表现为不明因素晕厥、严重的甚至表现为心肌梗死。然而在当下治疗中,PFO介入封堵治疗方法能够有效的改善其临床的症状,降低患者脑卒中的二次发生率。在此次研究中,选取……
