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黄芪辅助治疗伴糖尿病的精神分裂症患者对血糖水平影响

2019-02-16陈孔树,吴祖美

中外医疗 2019年35期

陈孔树,吴祖美

DOI:10.16662/j.cnki.1674-0742.2019.35.184

[摘要] 目的 分析黄芪辅助治疗伴糖尿病的精神分裂症患者对血糖水平影响。方法 方便选取102例2017年12月—2019年2月在该院治疗的伴糖尿病的精神分裂癥患者,两组患者均给予抗精神病药物治疗,将其随机分为对照组和观察组,各51例。给对照组给予胰岛素控制血糖,给观察组患者在对照组的基础上再联合黄芪治疗,观察并比较两组患者治疗前后血清SOD、HOMA-IR、FBG、2 hPG、HbAlc等水平的变化情况。 结果 治疗后,观察组SOD、FBG、2 hPG、FINS、HOMA-IR等指标分别为(108.31±19.0)NU/mL、(6.88±0.98)mmol/L、(8.31±1.09)mmol/L、(8.27±1.18)mU/L、(0.43±0.06),对照组分别为(88.21±12.88)NU/mL、(8.03±1.34)mmol/L、(11.26±1.36)mmol/L、(11.01±2.07)mU/L、(0.87±0.21),与对照组相比较差异有统计学意义(t=9.267、3.314、3.016、3.009、3.004,P<0.05 )。HbAlc水平,观察组为(8.03±2.05)%,对照组为(8.96±1.87)%,两组差异无统计学意义(t=0.214,P>0.05)。 结论 黄芪辅助治疗伴糖尿病的精神分裂症患者,能够有效改善患者的机体功能,降低患者的血糖水平,效果显著,有较高的推广价值。

[关键词] 黄芪;伴糖尿病的精神分裂症;血糖水平

[中图分类号] R749.3;R587.1          [文献标识码] A          [文章编号] 1674-0742(2019)12(b)-0184-03

Effect of Astragalus Membranaceus on Blood Glucose Level in Patients with Schizophrenia with Diabetes

CHEN Kong-shu1, WU Zu-mei2

1.Ningde Rehabilitation Hospital, Men's Three Wards (Men's 3), Ningde, Fujian Province, 352100 China;2.Department of Orthopaedics, 4th District, Ningde Hospital of Traditional Chinese Medicine, Ningde,Fujian Province, 352100 China

[Abstract] Objective To analyze the effect of astragalus on the treatment of blood glucose levels in patients with schizophrenia with diabetes. Methods Convenient selected a total of 102 patients with schizophrenia with diabetes mellitus who were treated in the hospital from December 2017 to February 2019 were enrolled. The patients in both groups were treated with antipsychotic drugs and randomly divided into control group and observation group. example. Insulin was administered to the control group to control blood glucose. The patients in the observation group were treated with jaundice on the basis of the control group. The changes of serum SOD, HOMA-IR, FBG, 2 hPG and HbAlc levels were observed and compared before and after treatment. Results After treatment, the indicators of SOD, FBG, 2 hPG, FINS and HOMA-IR in the observation group were (108.31±19.0) NU/mL, (6.88±0.98)mmol/L, (8.31±1.09)mmol/L, (8.27±1.18) mU/L, (0.43±0.06), the control group were (88.21±12.88) NU/mL, (8.03±1.34)mmol/L, (11.26±1.36)mmol/L, (11.01±2.07)mU/L, (0.87±0.21) were statistically different from the control group(t=9.267, 3.314, 3.016, 3.009, 3.004, P<0.05). HbAlc level, observation group was (8.03±2.05)%, control The group was(8.96±1.87)%, there was no  statistically significant difference between the two groups (t=0.214, P>0.05) . Conclusion Astragalus adjuvant treatment of patients with schizophrenia with diabetes can effectively improve the patient's body function. Reducing the patient's blood sugar level, the effect is significant, and has a high promotion value.

[Key words] Jaundice; Schizophrenia with diabetes; Blood sugar level

精神分裂症患者大都伴有血糖代谢的异常,对于伴有糖尿病的精神分裂症患者,临床上要在精神病药物治療的同时,给予控制血糖的治疗。黄芪具有明显的降血压、扩血管、改善微循环等作用,尤其在治疗糖尿病方面发挥出了越来越重要的作用[1-2]。有研究发现,中药黄芪降糖作用的发挥是通过增加组织对葡萄糖的摄取和利用进行介导的。该次对2017年12月—2019年2月期间51例给予抗精神病药物治疗的同时,增加了胰岛素联合了黄芪治疗后取得了较好的效果。具体报道如下。

1  资料与方法

1.1  一般资料

方便选取102例在该院治疗的伴糖尿病的精神分裂症患者。均符合《中国精神障碍分类与诊断标准》中精神分裂症的相关诊断标准[3]。……

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