郑晏群

[摘要] 目的 观察分析2型糖尿病患者脑出血后脑水肿应用甘油果糖联合吡拉西坦治疗的临床效果。方法 选取2017年1—12月收治的2型糖尿病脑出血后脑水肿患者76例，按抽签法分为参照组38例给予甘露醇治疗，实验组38例给予甘油果糖联合吡拉西坦治疗。比较两组颅内压降低幅度、治疗前后脑水肿体积、神经功能缺损状况和日常生活能力改善情况。结果 实验组治疗后颅內压降低幅度明显大于参照组（P<0.05）；两组治疗前脑水肿体积、NIHSS和BI评分比较差异无统计学意义（P>0.05）；经治疗后实验组脑水肿体积明显小于参照组，NIHSS评分明显低于参照组，BI评分明显高于参照组，差异有统计学意义（P<0.05）。结论 甘油果糖联合吡拉西坦治疗2型糖尿病脑出血后脑水肿效果确切，可有效降低患者颅内压，减轻脑水肿现象，有利于患者神经功能恢复，提高其生活质量。

[关键词] 2型糖尿病；脑出血；脑水肿；甘油果糖；吡拉西坦

[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062（2018）07（a）-0094-02

Clinical Observation on Glycerol Fructose Combined with Piracetam in Patients with Type 2 Diabetes Combined with Cerebral Edema after Cerebral Hemorrhage

ZHENG Yan-qun

Department of Neurology， Linyi Luozhuang Central Hospital， Linyi， Shandong Province， 276017 China

[Abstract] Objective To observe and analyze the clinical effect of glycerol fructose combined with piracetam in patients with type 2 diabetes combined with cerebral edema after cerebral hemorrhage. Methods 76 cases of patients with type 2 diabetes combined with cerebral edema after cerebral hemorrhage from January to December 2017 were selected and randomly divided into two groups with 38 cases in each， the control group were treated with mannitol， while the experimental group were treated with glycerol fructose combined with piracetam， and the differences in the decrease range of intracranial pressure， hydrocephalus volume before treatment， NIHSS and BI scores were compared. Results After treatment， the decrease range of intracranial pressure in the experimental group was obviously bigger than that in the control group（P<0.05）， the differences in the decrease range of intracranial pressure， hydrocephalus volume before treatment， NIHSS and BI scores between the two groups were not statistically significant（P>0.05）， after treatment， the hydrocephalus level in the experimental group after treatment was obviously lower than that in the control group， and the NIHSS score was obviously lower than that in the control group， and the BI score was obviously higher than that in the control group， and the difference was statistically significant（P<0.05）. Conclusion The effect of glycerol fructose combined with piracetam in patients with type 2 diabetes combined with cerebral edema after cerebral hemorrhage is definite， which can effectively reduce the intracranial pressure， relieve the encephaledema， help the recovery of nerve function， and improve the quality of life.

[Key words] Type 2 diabetes； Cerebral hemorrhage； Encephaledema； Glycerol fructose； Piracetam

近年来，随着人们生活质量的提升，饮食和生活习惯的改变，导致2型糖尿病也在不断的呈上升趋势[1]。2型糖尿病若病情得不到及时有效的控制，极有可能导致病患脑出血后脑水肿等严重并发症，甚至形成脑疝[2]。临床上多采用甘露醇对其进行治疗，但其治疗效果并不理想，为此，该文特对2017年1—12月甘油果糖联合吡拉西坦治疗2型糖尿病脑出血后脑水肿76例的临床效果进行了观察分析，现报道如下。

1 资料与方法

1.1 一般资料

选取该院收治的2型糖尿病脑出血后脑水肿患者76例，按抽签法分为参照组和实验组各38例，参照组男25例，女13例；年龄41～79岁，平均（62.4±6.3）岁；发病至就医时间2～13 h，平均（6.5±2.1）h。实验组男22例，女16例；年龄42～78岁，平均（62.8±6.5）岁；发病至就医时间2～14 h，平均（6.6±2.7）h。入选标准：均符合2型糖尿病诊断标准[3]，并经CT确诊为脑出血后脑水肿；……