王茜

[摘要] 目的 探讨头孢哌酮钠舒巴坦钠治疗糖尿病合并泌尿系统感染的临床疗效。方法 对该院2016年2月—2018年2月间收治的糖尿病合并泌尿系统感染患者92例进行回顾性分析，根据用药方法不同分为研究组（n=46）以及对照组（n=46）。对照组采取左氧氟沙星治疗，研究组给予头孢哌酮钠舒巴坦钠治疗，对比两组患者临床治疗效果。 结果 研究组总有效率（95.65%）较对照组总有效率（82.61%）更高，差异有统计学意义（P<0.05）；研究组不良反应发生率（6.52%）较对照组（21.74%）更低，差异有统计学意义（P<0.05）。经过治疗，两组患者空腹血糖、餐后2 h血糖均有所下降，差异有统计学意义（P<0.05），组间比较差异无统计学意义（P>0.05）。结论 头孢哌酮钠舒巴坦钠治疗糖尿病合并泌尿系统感染临床效果较优，不良反应较少，适用性较好。

[关键词] 头孢哌酮钠舒巴坦钠；糖尿病；泌尿系统感染

[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062（2018）08（a）-0081-02

Study on Curative Effect of Cefoperazone Sodium and Sulbactam Sodium in Treatment of Diabetes Combined with Urinary System Infection

WANG Qian

Endocrine Geriatrics Department， People's Hospital of Dali Bai Autonomous Prefecture， Dali， Yunnan Province， 671000 China

[Abstract] Objective To study the clinical curative effect of cefoperazone sodium and sulbactam sodium in treatment of diabetes combined with urinary system infection. Methods 92 cases of patients with diabetes combined with urinary system infection in our hospital from February 2016 to February 2018 were selected and divided into two groups with 46 cases in each according to different medication methods， the control group were treated with levofloxacin， while the research group were treated with cefoperazone sodium and sulbactam sodium， and the clinical treatment effect was compared between the two groups. Results The total effective rate in the research group was higher than that in the control group （95.65% vs 82.61%），the difference was statistically significant（P<0.05）， and the incidence rate of adverse reactions in the research group was lower than that in the control group （6.52% vs 21.74%）， the difference was statistically significant（P<0.05）， after treatment， the fasting blood glucose and postprandial 2 h blood glucose decreased in the two groups， the difference was statistically significant（P<0.05）， and the differences between groups were not statistically significant（P>0.05）. Conclusion The clinical effect of cefoperazone sodium and sulbactam sodium in treatment of diabetes combined with urinary system infection is better with fewer adverse reactions and better applicability.

[Key words] Cefoperazone sodium and sulbactam sodium； Diabetes； Urinary system infection

糖尿病是臨床常见的慢性疾病之一，是一种终生性疾病，尚不能根治，只能通过长期治疗控制病情发展。糖尿病患者常表现为多饮、多尿、多食以及疲倦，且免疫力低于正常群体。由于糖尿病患者尿液当中蛋白质、葡萄糖含量相对较高，会为细菌生长繁殖提供良好的条件，极可能造成尿路感染[1]。为探究糖尿病合并泌尿系统感染治疗方法，该院对2016年2月—2018年2月间收治的46例糖尿病合并泌尿系统感染患者采取了头孢哌酮钠舒巴坦钠治疗，获得了较好的效果，现报道如下。

1 资料与方法

1.1 一般资料

纳入标准[2]：所选入患者均符合糖尿病合并泌尿系统感染相关诊断标准，研究实施前已取得患者及其家属同意，并签署知情同意书。

排除标准[2]：存在其他器官如心、肝、肾等功能障碍者；……