肖静 黄佳 郭晨 江如

[摘要]目的 探讨维生素E治疗子宫内膜异位症盆腔疼痛的临床价值。方法 选取2016年2月～2017年5月我院收治的60例伴有盆腔疼痛的子宫内膜异位症患者作为研究对象，按照简单随机化法将其分为实验组（n=30）和对照组（n=30）。对照组患者给予屈螺酮炔雌醇片治疗，实验组患者在对照组的基础上，同时给予维生素E治疗。比较两组患者治疗后的痛经评分、性交痛评分、盆腔疼痛评分以及不良反应情况。结果 两组患者治疗后的痛经评分、性交痛评分、盆腔疼痛评分均低于治疗前，差异有统计学意义（P<0.05）；实验组患者治疗后的盆腔疼痛评分显著低于对照组，差异有统计学意义（P<0.05）。两组患者用药期间的不良反应总发生率比较，差异无统计学意义（P>0.05）。结论 维生素E治疗子宫内膜异位症盆腔疼痛，可减轻患者的疾病症状，改善其预后。

[关键词]维生素E；子宫内膜异位症；盆腔疼痛

[中图分类号] R711.7 [文献标识码] A [文章编号] 1674-4721（2018）8（c）-0127-03

[Abstract] Objective To explore the clinical value of Vitamin E in the treatment of pelvic pain caused by endometriosis. Methods Altogether 60 patients with endometriosis and accompanied with pelvic pain who were treated in our hospital from February 2016 to May 2017 were selected as objects and divided into experiment group （n=30） and control group （n=30） according to the simple randomization method. The control group was treated with Drospirenone and Ethinylestradiol Tablets， while the experiment group was treated with Vitamin E on the basis of the control group. The dysmenorrhea scores， intercourse pain scores， pelvic pain scores and adverse reactions after treatment were compared between two groups. Results The scores of dysmenorrhea， intercourse pain and pelvic pain after treatment in two groups were lower than those before treatment， with statistically significant differences （P<0.05）. The score of pelvic pain after treatment in the experiment group was significantly lower than that in the control group， with statistically significant difference （P<0.05）. There was no significant difference in the total incidence of adverse reactions between two groups （P>0.05）. Conclusion Application of Vitamin E in the treatment of pelvic pain caused by endometriosis can reduce the patients′ symptoms and improve their prognosis.

[Key words] Vitamin E； Endometriosis； Pelvic pain

子宮内膜异位症（EMS）具有较高的发生率，在10%左右，尤其在不孕症女性中，EMS的发生率在25%～40%[1]。EMS患者的主要表现症状为性交困难、不孕、盆腔疼痛等[2]。研究显示，40%以上的EMS患者存在盆腔疼痛，而70%的盆腔疼痛患者合并EMS。有研究显示，EMS与自由基之间存在一定的联系，采用抗氧化剂为患者实施治疗，可减轻患者盆腔疼痛的程度，具有较好的治疗效果。本研究选取我院收治的60例EMS患者作为研究对象，旨在探究EMS盆腔疼痛患者接受维生素E治疗的价值，现报道如下。

1资料与方法

1.1一般资料

选取2016年2月～2017年5月我院收治的60例伴有盆腔疼痛的EMS患者作为研究对象。纳入标准：①经病理学检查确诊为EMS者；②合并性交痛、痛经以及反复性盆腔痛者；……