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季德胜蛇药片联合龙葵浸膏治疗蛇咬伤的疗效观察

2018-11-07吴红涛

上海医药 2018年25期

吴红涛

摘 要 目的:观察龙葵浸膏联合抗季德胜蛇药片治疗蛇咬伤的疗效。方法:选取我院2015年1月—2017年11月收治的蛇咬伤患者68例为研究对象,按照随机方法分为对照组和观察组各34例,对照组给予常规治疗,观察组在对照组基础上使用季德胜蛇药片联合龙葵浸膏外敷治疗,观察比较两组的临床效果。结果:对两组患者肢体肿胀程度及进行比较,治疗组显著好于对照组,差异具有统计学异议(P<0.05)。两组患者治疗WBC、CK、CK-MB较治疗前明显下降(P<0.05),且观察组WBC、CK、CK-MB水平优于对照组(P<0.05)。结论:季德胜蛇药片联合龙葵浸膏治疗蛇咬伤可显著改善肢体肿胀,减轻病情。

关键词 龙葵浸膏 季德胜蛇药片 蝮蛇咬伤 临床效果

中图分类号:R286; R646 文献标志码:A 文章编号:1006-1533(2018)S1-0025-03

Curative effect of Jidesheng antivenom tablets combined with extracts of Solanum nigrum on snake bite

WU Hongtao

(Department of Emergency, The 44th Hospital of PLA, Guiyang 550009, China)

AbstrAct objective: To observe the clinical effect of Jidesheng antivenom tablets combined with extracts of Solanum nigrum on the bites of Agkistrodon halys. Methods: Sixty-eight patients with snake bite admitted in our hospital from January, 2015 to November, 2017 were randomly divided into a control group and an observation group with 34 cases each. The control group underwent routine treatment while the observation group was additionally treated with external application of Jidesheng antivenom tablets combined with extract of Solanum nigrum. The clinical effects were compared between the two groups. results: The degree of limb swelling was much better in the observation group than the control group (P<0.05). WBC, CPR, CK and CKMB were significantly decreased after treatment than before(P<0.05), and their levels were much better in the observation group than the control group (P<0.05). conclusion: Jidesheng antivenom tablets combined with extracts of Solanum nigrum for the treatment of bites of Agkistrodon halys can effectively improve limb swelling and reduce the condition.

Key worDs Jidesheng antivenom tablets; Solanum nigrum; agkistrodon bites; clinical effect

蛇咬伤是医院急诊科常见的急危重症,也是高原、丛林等特殊环境中作业时遭遇的有毒有害动植物因素中的常见因素之一。由于我省地处祖国西南,以山区及丘陵地貌居多,植被丰富,气候温暖潮湿,地方群众于野外作业多在夏秋两季,是爬行类动物活动及生长繁衍的活跃时期,因此对蛇咬伤的综合防治提出了更高的要求。自2017年起,我科使用季德胜蛇药片联合龙葵浸膏治疗蛇咬伤68例,大部分取得了良好的疗效。

1 资料与方法

1.1 一般资料

选取我院2015年1月—2017年11月收治的蛇咬伤患者68例为研究对象,就诊时间均为伤后12 h之内,咬伤部位均为四肢咬伤。将68例患者按随机法分为观察组和对照组,其中观察组34例患者中,男性28例,女性6例,年龄12~68 岁。对照组34例患者中男性26例,女性8例,年龄12~65 岁。两组患者的一般治疗比较差异无统计学意义(P>0.05),具有可比性。

1.2 方法

两组患者均给予常规治疗,例如注射抗蝮蛇毒血清、抗感染、破伤风抗毒素血清注射、患肢穴位切開、维持水电解质酸碱平衡、使用肾上腺皮质激素(地塞米松磷酸钠注射液10 mg加入5%葡萄糖液500 ml,静滴)。……

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