梅帆　朱斌

【摘要】 目的：分析临床小儿心律失常接受门冬氨酸钾镁治疗的临床效果。方法：选取2015年10月-2017年10月本院收治的120例心律失常患儿参与研究，根据不同治疗方法分为观察组与对照组，每组60例。对照组接受基础常规治疗，观察组在基础常规治疗上联合门冬氨酸钾镁治疗。比较两组临床治疗效果。结果：治疗14 d后，观察组治疗总有效率95.00%高于对照组80.00%，差异有统计学意义（字2=6.171 4，P=0.013 0）。治疗14 d后，观察组早搏频率低于对照组，差异有统计学意义（P<0.05）。观察组不良反应发生率为3.33%，与对照组5.00%比较，差异无统计学意义（字2=0.208 7，P=0.647 8）。结论：小儿心律失常接受门冬氨酸钾镁治疗能够明显提升用药效果，使患儿临床症状明显改善，显著降低早搏频率，值得临床推广应用。

【关键词】 小儿心律失常； 门冬氨酸钾镁； 早搏

Clinical Efficacy of Potassium Magnesium Aspartate in Treatment of Arrhythmias in Children/MEI Fan，ZHU Bin.//Medical Innovation of China，2018，15（17）：0-098

【Abstract】 Objective：To analyze the clinical effect of Potassium Magnesium Aspartate in the treatment of arrhythmias in children.Method：120 children with arrhythmia were selected from October 2015 to October 2017，according to different treatment method，they were divided into observation group and control group，60 cases in each group.The control group was received routine treatment，the observation group was received routine treatment and Potassium Magnesium Aspartate.The clinical effects were compared between the two groups.Result：14 days after treatment，the total effective rate in observation group was 95.00%，which was higher than 80.00% in control group，the difference was statistically significant（字2=6.171 4，P=0.013 0）.After 14 days of treatment，the frequency of premature beats in the observation group was lower than that in the control group（P<0.05）.The incidence of adverse reactions in the observation group was 3.33%，compared with 5.00% of the control group，there was no significant difference（字2=0.208 7，P=0.647 8）.Conclusion：The treatment of children with arrhythmias by Potassium Magnesium Aspartate can obviously improve the clinical symptoms and reduce the frequency of premature beats，it is worthy of clinical popularization and application.

【Key words】 Arrhythmias in children； Potassium Magnesium Aspartate； Premature beat

First-authors address：The First Peoples Hospital of Xiangyang Affiliated to Hubei Medical College，Xiangyang 441000，China

doi：10.3969/j.issn.1674-4985.2018.17.025

小兒是心律失常的主要发病群体，不同类型心源性疾病都可能出现心律失常，另外部分非心源性疾病也可能出现心律失常，甚至健康小儿部分时候也会出现心律失常表现[1-2]。一些心律失常患儿初期症状表现不明显，大多是由于出现上呼吸道感染后受检发现，基本都是功能性心律失常，分析是由于小儿心脏自主神经功能缺乏足够稳定性，所以随着心脏发育逐渐完善，这一症状会逐渐消失[3-4]。不过也有一些小儿心律失常是因为后天疾病造成，常见的为病毒性心肌炎导致的心律失常，假设患儿没有接受及时治疗，病情会逐渐加重，严重情况下会对生命安全造成威胁[5-6]。临床针对小儿心律失常的常规治疗难以获得满意的远期效果，治疗后出现复发的可能性很大[7]，本院对2015年10月-2017年10月60例心律失常患儿采用门冬氨酸钾镁治疗，取得了满意的临床效果，现将结果报道如下。……