拜糖平联合门冬胰岛素30治疗2型糖尿病的疗效观察
2018-08-23舒立极
舒立极
[摘要] 目的 探讨拜糖平联合门冬胰岛素30治疗2型糖尿病的临床疗效。方法 选取2016年8月—2017年6月期间在该院接受治疗的100例2型糖尿病患者作为研究对象,对照组患者采取门冬胰岛素30单纯治疗方案,观察组患者采取拜糖平+门冬胰岛素30综合治疗方案,门冬胰岛素30诊治方式与对照组等同,但三餐饭前需嚼服拜糖平,主要比较2组患者FPG、2 hPG及不良反应状况。结果 与治疗前相比,2组FPG和2 hPG都有所下降(P<0.05),治疗效果取得一定成效。而在诊治后,观察组FPG和2 hPG下降程度更为明显(P<0.05)。2组患者均产生了不良反应现象,两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论 拜糖平联合门冬胰岛素30治疗2型糖尿病效果显著且降低了低血糖发生风险,因此,在临床中能够大力实践、推广。
[关键词] 拜糖平;门冬胰岛素30;2型糖尿病
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2018)02(b)-0005-02
Effect of Beribavi and Aspart 30 on Type 2 Diabetes Mellitus
SHU Li-ji
Department of Endocrinology, Yangxin County People's Hospital, Yangxin, Hubei Province, 435200 China
[Abstract] Objective This paper tries to explore the clinical efficacy of beribavi and insulin aspart 30 in the treatment of type 2 diabetes. Methods 100 patients with type 2 diabetes who were treated in this hospital from August, 2016 to June, 2017 were selected, the patients in the control group took the insulin 30 simple treatment program and the patients in the observation group took “beribavi + aspart insulin 30" comprehensive treatment plan, insulin aspart 30 was equivalent with the control group, but before the three meals, the subjects needed to chew beribavi, mainly comparing the two groups of patients of FPG, 2 hPG blood glucose control and adverse reactions. Results Compared with that before treatment, FPG and 2 hPG in both groups decreased (P<0.05), and the treatment effect achieved certain results. After diagnosis and treatment, the decrease of FPG and 2 hPG in the observation group was more obvious(P<0.05). The adverse reactions occurred in both groups. There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusion The combination of beribavi and insulin aspart 30 is effective in treating type 2 diabetes and reduces the risk of hypoglycemia. Therefore, it can be practiced and promoted in clinical practice.
[Key words] Beribavi; Insulin 30; Type 2 Diabetes
2型糖尿病是臨床常见疾病,据临床研究表明,2型糖尿病发病因素主要受饮食习惯、体力运动及增龄影响,而高血脂、高血压会增加患病风险[1]。对于轻微2型糖尿病患者,采取饮食控制或适当运动即可控制病情[2]。而在治疗疗效不显著下,就要采取药物治疗手段[3]。该研究选取2016年8月—2017年6月期间在该院接受治疗的100例2型糖尿病患者作为研究对象, 探讨拜糖平联合门冬胰岛素30治疗2型糖尿病的临床疗效。
1 对象与方法
1.1 研究对象
选取在该院接受治疗的100例2型糖尿病患者作为研究对象。全部患者均符合世界卫生组织(WHO)对2型糖尿病的评定标准[4]。按照随机、均衡理念,对照组患者男24例,女26例;年龄32~68岁,平均年龄(37.67±2.31)岁;病程2~7年,平均病程(2.3±2.7)年。观察组男27例,女23例;年龄34~70岁,平均年龄(39.34±4.67)岁。病程1~6年,平均病程(2.7±2.5)年。……
