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后腹腔镜肾部分切除术治疗多房囊性肾癌13例报告

2018-06-20杨风光黄超许清江余成波

中外医疗 2018年7期
关键词:诊断腹腔镜

杨风光 黄超 许清江 余成波

[摘要] 目的 探讨后腹腔镜肾部分切除术治疗多房囊性肾癌的可行性。方法 回顾性分析2010年6月—2016年6月福建省立医院治疗的13例多房囊性肾癌的临床资料,分析其手术方式、病理和预后特点。结果 11例成功行腹腔镜肾部分切除术,2例改行开放肾部分切除术。平均手术时间(122.8±21.0)min,平均冷缺血时间(26.5±7.6)min,术中平均失血量(109.3±52.5)mL,术后分期10例为T1a,3例T1b。术前和术后3个月血肌酐差异无统计学意义(t=0.577,P>0.05),术后患肾eGFR为(39.3±7.2)mL/min,较术前下降约17.9%,差异有统计学意义(t=2.523,P<0.05)。平均随访27.3个月,无肿瘤复发及转移。结论 后腹腔镜肾部分切除术是治疗多房囊性肾癌安全有效的方法。

[关键词] 多房囊性肾癌;诊断;肾部分切除术;腹腔镜

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2018)03(a)-0039-03

Retroperitoneal Nephrectomy for the Treatment of 13 Cases of Polycystic Kidney Disease

YANG Feng-guang, HUANG Chao, XU Qing-jiang, YU Cheng-bo

Fujian Provincial Clinical College of Fujian Medical University,(Fujian Provincial Hospital),Department of Urology, Fuzhou, Fujian Province, 350001 China

[Abstract] Objective This paper tries to report the perioperative outcomes of retroperitoneal laparoscopic partial nephrectomy (RLPN) for multilocular cystic renal cell carcinoma (MCRCC) and to evaluate the feasibility of this technique. Methods The clinical data of 13 cases of multilocular renal cell carcinoma treated in Fujian Provincial Hospital from June 2010 to June 2016 were retrospectively analyzed, and their surgical methods, pathology and prognosis were analyzed. Results 11 patients were performed RLPN successfully, 2 patients were converted to open partial nephrectomy. The mean operative time was(122.8±21.0)min, mean cold ischemia time(CIT) was (26.5±7.6)min, and the mean estimated blood loss was (109.3±52.5)mL. Pathologically of 10 cases of the tumors presented as stage T1a, and 3 cases presented as stage T1b. There were no difference in serum creatinine change before and after operation(t=0.577, P>0.05), post-operation estimated glomerular filtration rate (eGFR) were (39.3±7.2)mL/min in diseased side, which were declined significantly (17.9%) when compared to pre-operation(t=2.523, P<0.05). No recurrences or new lesions occurred at a mean follow-up time of 27.3 months. Conclusion RLPN should be regarded as the preferred surgical technique for MCRCC.

[Key words] Polycystic kidney disease; Diagnosis; Partial nephrectomy; Laparoscopy

多房囊性腎癌(Muiltlocularcysticrenalcellcarcinoma,MCRCC)是肾癌的少见类型,通常分级及分期均较低,预后良好,而且肿瘤的大小不影响预后。MCRCC采用保肾手术特别是采用腹腔镜行肾部分切除时,存在穿破肿瘤导致术后种植,巨大肿瘤切除困难等特点,手术难度较高。该文回顾性分析福建省立医院泌尿外科从2010年6月—2016年6月采用后腹腔镜肾部分切除术(retroperitoneal laparoscopic partial nephrectomy, RLPN)治疗的多房囊性肾癌13例,探讨腹腔镜手术的安全性和可行性,现报道如下。

1 资料与方法

1.1 一般资料

方便选取的该组患者13例,男性9例,女性4例,年龄35~71岁,平均(47.6±11.6)岁。肿瘤位置:左侧8例,右侧5例;上极5例,下极5例,中部3例。肿瘤大小2.3~6.8 cm,平均(3.2±1.9)cm。影像学检查偶然发现11例,腰背痛1例,腰痛伴肉眼血尿 1例。在使用患者各种资料时,均获得患者的同意,并通过伦理委员会的批准。

1.2 检查方法

所有病例均行薄层CT增强扫描、 CTA血管重建和超声造影检查。CT表现为球型或椭圆形病变,囊壁厚薄不均,囊壁结节多<5 mm,增强期分隔和结节不同程度强化。按……

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