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宫腔镜治疗宫腔因素所致不孕不育患者的生殖预后效果

2018-04-26张瑶瑶钟龚乐

中国当代医药 2018年5期

张瑶瑶 钟龚乐

[摘要]目的 探讨宫腔镜治疗宫腔因素所致不孕不育患者生殖预后的效果。方法 选取2016年1月~2017年1月我院收治的46例因宫腔因素所致的不孕不育患者作为研究对象,给予宫腔镜辅助手术治疗,记录采取宫腔镜检查与治疗前后患者的宫腔因素占比,并评价术后患者的生殖预后状况。结果 患者治疗后的子宫内膜息肉、息肉样增生、宫腔粘连比例明显低于治疗前,差异有统计学意义(P<0.05)。46例患者中,妊娠率为73.9%,流产率为20.0%,早产或未妊娠率为6.5%。结论 采用宫腔镜辅助手术治疗宫腔因素所致的不孕不育患者,能大幅度改善患者的妊娠结局与患者的生殖预后,值得在临床进一步推广研究。

[关键词]宫腔镜;宫腔因素;不孕不育;生殖预后;妊娠

[中图分类号] R711.6 [文献标识码] A [文章编号] 1674-4721(2018)2(b)-0059-03

Effect of reproductive prognosis in infertile patients caused by intrauterine factors after hysteroscopic treatment

ZHANG Yao-yao ZHONG Gong-le

Dongguan Kanghua Hospital in Guangdong Province,Dongguan 523080,China

[Abstract]Objective To investigate the effect of reproductive prognosis in infertility caused by intrauterine factors.Methods 46 cases of infertility caused by intrauterine factors treated in our hospital from January 2016 to January 2017 were selected as the subjects.The operation for the above patients was performed under the assistance of hysteroscopy.The proportion of intrauterine factors in patients with hysteroscopy before and after treatment was recorded,and the prognosis of the patients was evaluated.Results The proportion of endometrial polyps,polypoid hyperplasia and intrauterine adhesions in patients after treatment was significantly lower than that before treatment,the difference was statistically significant (P<0.05).In 46 cases of patients,the pregnancy rate was 73.9%,the abortion rate was 20.0%,the preterm birth rate or the pregnancy rate was 6.5%.Conclusion Hysteroscopy assisted surgery for infertility caused by intrauterine factors,can significantly improve the patient′s pregnancy outcome,enhance the patient′s reproductive prognosis,which is worthy of further promotion in clinical research.

[Key words]Hysteroscopy;Intrauterine factors;Infertility;Reproductive prognosis;Pregnancy

隨着生活节奏的加快和性传统疾病的传播,适龄女性出现不孕不育症的概率逐年升高,其发生率已接近15%,严重影响家庭的和睦与社会的发展[1]。其中,宫腔因素是引起女性不孕不育的重要原因之一[2]。如何减轻宫腔因素的危害、改善患者的病情状况、增强生殖预后的效果,已成为临床面临的重要课题[3]。手术治疗及保守治疗是解决该问题的方法,如临床结合宫腔镜进行手术治疗,能准确诊断临床中的异常情况,具有安全、有效的特点[4-5]。本研究选取我院收治的46例宫腔因素所致的不孕不育患者作为研究对象,旨在探讨宫腔镜的临床应用价值,现报道如下。

1资料与方法

1.1一般资料

选取2016年1月~2017年1月我院收治的46例宫腔因素所致的不孕不育患者作为研究对象,所有患者均经宫腔镜与病理检查确诊为不孕不育患者。患者年龄22~38岁,平均(28.34±2.63)岁,病程2~8年,平均(3.43±1.45)年。宫腔因素包括:子宫内膜结核、子宫黏膜下肌瘤、子宫纵膈、子宫内膜息肉、息肉样增生、宫腔粘连。……

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