邱燕霞

[摘要] 目的 对盐酸氨溴索治疗小儿毛细支气管炎的临床效果进行探讨。方法 随机选取该院2014年6月—2017年6月期间所收治的100例小儿毛细支气管炎患儿作为该次研究对象，对患儿进行随机分组治疗，每组50例，对照组采取抗感染与抗病毒等对症处理，研究组在此基础上加用盐酸氨溴索治疗，对比分析两组患儿的治疗效果与平均住院时间。结果 研究组治疗效果显著优于对照组，治愈率为60.00%，总有效率为96.00%，明显高于对照组（38.00%，82.00%），两组差异有统计学意义（P<0.05），研究组的平均住院时间（7.21±3.05）d，显著高于对照组（10.87±3.59）d，兩组差异有统计学意义（P<0.05）；研究组的氧疗时间为（2.24±1.62）d，对照组的氧疗时间为（4.52±2.05）d，研究组的哮鸣音时间为（3.15±1.21）d，对照组的哮鸣音时间为（4.58±1.32）d，研究组的湿啰音时间为（4.89±1.48）d，对照组的湿啰音时间为（5.94±1.99）d，在肺部哮鸣音、氧疗时间、湿啰音方面，研究组与对照组相比，差异有统计学意义（P<0.05）。 结论 将盐酸氨溴索应用在小儿毛细支气管炎中的效果显著，具有快速缓解患儿临床症状的特点，且治愈率极高，不失为一种有效、安全的治疗手段。

[关键词] 盐酸氨溴索；小儿毛细支气管炎；临床效果

[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-0742（2017）08（a）-0132-03

[Abstracts] Objective This paper tries to investigate the clinical effect of ambroxol hydrochloride in children with bronchiolitis. Methods 100 children with bronchiolitis from June 2014 to June 2017 were random selected and randomly divided into the control group and the study group， with 50 cases in each group. The control group adopted infection and antiviral treatment， the study group added ambroxol hydrochloride treatment， the curative effects and the average hospitalized time of the two groups were compared. Results The treatment effect of the study group was significantly better than the control group， with the cure rate of 60.00%， total effective rate of 96.00%， significantly higher than control group of 38.00% and 82.00%， and the differences between the two groups were significant； average length of hospital stay in the study group was （7.21±3.05）days， significantly higher than that of control group of （10.87±3.59）days， the difference in the two groups was significant （P<0.05）； the oxygen cure time of the study group was （2.24±1.62）days， and that of the control group was （4.52±2.05） days， the wheezing sound time of the study group was （3.15±1.21）days， that of the control group was （4.58±1.32）days， the moist rale time of the study group was （4.89±1.48） days， and that of the control group was （5.94±1.99）days， there were significant differences in the areas of lung asthma， oxygen therapy and moist rale（P<0.05）. Conclusion The effect of ambroxol hydrochloride in children with bronchiolitis is remarkable， which can rapidly relieve clinical symptoms in children and whose curative effect is outstanding. It is an effective and safe treatment.

[Key words] Ambroxol hydrochloride； Pediatric bronchiolitis； Clinical effect

小儿毛细支气管炎是指毛细支气管出现炎症情况，毛细支气管炎患儿的主要病变部位是肺部的细小支气管，对毛细支气管炎患儿的机体健康带来较大威胁。毛细支气管炎属于幼儿在冬春季节常见疾病，当前临床治疗中主要是对其进行消炎治疗，以此改善患儿通气，解除患儿呼吸道阻塞的临床症状[1]，该文主要通过对该院在2014年6月—2017年6月期间所收治200例小儿毛细支气管炎患儿进行研究，分别以常规治疗和盐酸氨溴索治疗，现报道如下。endprint

1 资料与方法

1.1 一般资料

随机选取该院所收治的100例小儿毛细支气管炎患儿作为该次研究对象，对患儿进行随机分组治疗，每组50例，所有患儿均符合小儿毛细支气管炎的诊断标准[2]，所有患儿及家属均已签订知情同意书，患儿中无呼吸衰竭以及先天性喘病等疾病。研究组患儿中男26例，女24例，最大年龄22个月，最小年龄8个月，中位年龄（12±3）个月；……